Characteristics of patients with increasing COPD assessment test scores within 3 years

Hidehiro Irie, Shotaro Chubachi, Minako Sato, Akihiro Tsutsumi, Ichiro Nakachi, Naoki Miyao, Kazumi Nishio, Hidetoshi Nakamura, Koichiro Asano, Tomoko Betsuyaku

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Background The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a subjective measure of quality of life. The aim of this study was to examine the characteristics of COPD patients with increasing CAT scores within 3 years. Methods Keio University and its affiliate hospitals conducted an observational COPD cohort study over 3 years. St. George's Respiratory Questionnaire (SGRQ) and CAT were completed at baseline and annually thereafter. Patients who had at least 3 CAT scores were included (n = 315). The ΔCAT score/year and ΔSGRQ score/year were calculated by the slope between each of the measures and the date of measurement. Results The median ΔCAT score/year was 0.4, and ΔCAT score/year was significantly correlated with ΔSGRQ total score/year. Using an annual cut-off CAT score of +2 points, patients who deteriorated (n = 79) were older, had lower %FEV1, and more severe emphysema on computed tomography scan at baseline than patients who did not deteriorate. The baseline value was not a determinant of subsequent changes in the CAT score. Longitudinal changes in the CAT score were positively correlated with those in the SGRQ score. Conclusions Old age and severe COPD, not the CAT score at one time point, predicted worsening quality of life.

Original languageEnglish
Pages (from-to)101-108
Number of pages8
JournalRespiratory Medicine
Publication statusPublished - 2017 Oct


  • COPD
  • Emphysema
  • Quality of life

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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