Chikungunya fever in Japan imported from the Caribbean Islands

Kazuo Imai, Eri Nakayama, Takuya Maeda, Kei Mikita, Yukiko Kobayashi, Aoi Mitarai, Yasuko Honma, Satoru Miyake, Koki Kaku, Yasushi Miyahira, Akihiko Kawana

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


A 53-year-old Japanese woman who was working as a volunteer in the Commonwealth of Dominica in the Caribbean islands presented with a high-grade fever and severe incapacitating generalized arthralgia. The Asian genotype of the chikungunya virus was confirmed using reverse transcription- PCR and serology, based on the presence of a specific neutralization titer and immunoglobulin M antibodies. She was diagnosed with post-chikungunya chronic arthritis based on persistence of her polyarthritis for 3 months and the presence of rheumatoid factor, immunoglobulin G-rheumatoid factor, and matrix metalloproteinase-3. Chikungunya virus should be considered as a causative pathogen in travelers returning from Caribbean islands. Clinicians should consider chikungunya fever in the differential diagnosis of patients who complain of chronic arthritis and have a history of travel to an endemic area.

Original languageEnglish
Pages (from-to)151-153
Number of pages3
JournalJapanese Journal of Infectious Diseases
Issue number2
Publication statusPublished - 2016 Mar 23
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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