TY - JOUR
T1 - Chrono-exercise
T2 - Time-of-day-dependent physiological responses to exercise
AU - Kim, Hyeon Ki
AU - Radak, Zsolt
AU - Takahashi, Masaki
AU - Inami, Takayuki
AU - Shibata, Shigenobu
N1 - Funding Information:
This work was supported by the Japan Society for the Promotion of Science (KAKENHI grant numbers 20K19689 and 18K17940 to H.-K. K. and 19H01089 to S.S. ) and the JST-Mirai Program (grant number JMPJM120D5 ) to S.S.
Publisher Copyright:
© 2022 Chengdu Sport University
PY - 2023/3
Y1 - 2023/3
N2 - Exercise is an effective strategy to prevent and improve obesity and related metabolic diseases. Exercise increases the metabolic demand in the body. Although many of the metabolic health benefits of exercise depend on skeletal muscle adaptations, exercise exerts many of its metabolic effects through the liver, adipose tissue, and pancreas. Therefore, exercise is the physiological state in which inter-organ signaling is most important. By contrast, circadian rhythms in mammals are associated with the regulation of several physiological and biological functions, including body temperature, sleep-wake cycle, physical activity, hormone secretion, and metabolism, which are controlled by clock genes. Glucose and lipid tolerance reportedly exhibit diurnal variations, being lower in the evening than in the morning. Therefore, the effects of exercise on substrate metabolism at different times of the day may differ. In this review, the importance of exercise timing considerations will be outlined, incorporating a chrono-exercise perspective.
AB - Exercise is an effective strategy to prevent and improve obesity and related metabolic diseases. Exercise increases the metabolic demand in the body. Although many of the metabolic health benefits of exercise depend on skeletal muscle adaptations, exercise exerts many of its metabolic effects through the liver, adipose tissue, and pancreas. Therefore, exercise is the physiological state in which inter-organ signaling is most important. By contrast, circadian rhythms in mammals are associated with the regulation of several physiological and biological functions, including body temperature, sleep-wake cycle, physical activity, hormone secretion, and metabolism, which are controlled by clock genes. Glucose and lipid tolerance reportedly exhibit diurnal variations, being lower in the evening than in the morning. Therefore, the effects of exercise on substrate metabolism at different times of the day may differ. In this review, the importance of exercise timing considerations will be outlined, incorporating a chrono-exercise perspective.
KW - Chrono-exercise
KW - Circadian rhythm
KW - Energy metabolism
KW - Exercise timing
KW - Inter-organ communication
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U2 - 10.1016/j.smhs.2022.11.003
DO - 10.1016/j.smhs.2022.11.003
M3 - Review article
AN - SCOPUS:85144918474
SN - 2666-3376
VL - 5
SP - 50
EP - 58
JO - Sports Medicine and Health Science
JF - Sports Medicine and Health Science
IS - 1
ER -
