Clinical application of sentinel node navigation surgery for esophageal cancer

Hiroya Takeuchi, Yoshirou Saikawa, T. Oyama, Y. Kitagawa

Research output: Contribution to journalReview articlepeer-review


In esophageal cancer, sentinel nodes (SNs) are identified as multiple nodes and widely spread from cervical to abdominal areas. In more than 80% of the cases, at least one SN is located in the 2nd or 3rd compartment of regional lymph nodes which have been considered to be "skip metastases". This characteristic distribution of SNs is attributed to the multi-directional lymphatic drainage routes from the esophagus. Clinical application of SN navigation surgery will be expected to play a key role for intraoperative diagnosis for lymph node metastasis and individualized multimodal therapy in patients with cT1N0 esophageal cancer.

Original languageEnglish
Pages (from-to)749-753
Number of pages5
JournalKyobu geka. The Japanese journal of thoracic surgery
Issue number8 Suppl
Publication statusPublished - 2009 Jul

ASJC Scopus subject areas

  • Medicine(all)


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