Clinical evaluation of the Smart Plug™ in the treatment of dry eyes

Takashi Kojima, Murat Dogru, Reiko Ishida, Eiki Goto, Yukihiro Matsumoto, Kazuo Tsubota

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


PURPOSE: To evaluate the efficacy of a thermo sensitive punctum plug, the Smart Plug™, in the treatment of dry eyes. DESIGN: Observational case-series study. METHODS: Eighteen eyes of 10 dry eye patients who previously failed conventional plug insertion were enrolled. Schirmer 1 test, vital staining scores, and tear clearance tests were performed before plug insertion, at 2 weeks, 1 month, and 3 months after insertion. RESULTS: Although Schirmer test values were not significantly different before and after plug insertion, the tear clearance rate considerably decreased (Before insertion: 14.8 ± 11.4; After insertion: 8.2 ± 6.6) (P < .05). Rose-Bengal and fluorescein scores improved significantly after plug insertion (Rose-Bengal: Before insertion: 6.4 ± 2.0; After insertion: 3.3 ± 1.6 points, Fluorescein: Before insertion: 4.8 ± 2.3; After insertion: 2.1 ± 1.3) (P < .05). No complications were observed. CONCLUSIONS: Smart Plug™ proved to be a safe and efficient option in the treatment of dry eye.

Original languageEnglish
Pages (from-to)386-388
Number of pages3
JournalAmerican Journal of Ophthalmology
Issue number2
Publication statusPublished - 2006 Feb
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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