TY - JOUR
T1 - Clinical information on serum IGFBP-3 levels and IGFBP-3 proteolytic activity in childhood
AU - Hasegawa, Yukihiro
AU - Hasegawa, Tomonobu
AU - Fujii, Katsura
AU - Konii, Hideko
AU - Anzo, Makoto
AU - Aso, Taiji
AU - Kotoh, Shinobu
AU - Tsuchiya, Yutaka
PY - 1995
Y1 - 1995
N2 - In this review paper, three pieces of clinical information in childhood are presented: (1) IGFBP-3 may replace GH provocation tests in the diagnosis of GH deficiency (GHD); (2) IGFBP-3 levels are regulated by IGF-I levels in a short period, and (3) ratio of free IGF-I to total IGF-I is high in serum of early infancy, similarly to serum of pregnancy, only partially owing to the presence of IGFBP-3 proteolytic activity. Each paper will be published soon.
AB - In this review paper, three pieces of clinical information in childhood are presented: (1) IGFBP-3 may replace GH provocation tests in the diagnosis of GH deficiency (GHD); (2) IGFBP-3 levels are regulated by IGF-I levels in a short period, and (3) ratio of free IGF-I to total IGF-I is high in serum of early infancy, similarly to serum of pregnancy, only partially owing to the presence of IGFBP-3 proteolytic activity. Each paper will be published soon.
KW - IGFBP-3
KW - IGFBP-3 proteolytic activity
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U2 - 10.1016/0955-2235(96)00005-1
DO - 10.1016/0955-2235(96)00005-1
M3 - Article
C2 - 8817690
AN - SCOPUS:0029434890
SN - 0955-2235
VL - 6
SP - 457
EP - 463
JO - Progress in Growth Factor Research
JF - Progress in Growth Factor Research
IS - 2-4
ER -