TY - JOUR
T1 - Clinical practice recommendations for the diagnosis and management of human herpesvirus-6B encephalitis after allogeneic hematopoietic stem cell transplantation
T2 - the Japan Society for Hematopoietic Cell Transplantation
AU - Ogata, Masao
AU - Uchida, Naoyuki
AU - Fukuda, Takahiro
AU - Ikegame, Kazuhiro
AU - Kamimura, Tomohiko
AU - Onizuka, Makoto
AU - Kato, Koji
AU - Kobayashi, Hikaru
AU - Sasahara, Yoji
AU - Sawa, Masashi
AU - Sawada, Akihisa
AU - Hasegawa, Daiichiro
AU - Masuko, Masayoshi
AU - Miyamoto, Toshihiro
AU - Okamoto, Shinichiro
N1 - Publisher Copyright:
© 2019, The Author(s), under exclusive licence to Springer Nature Limited.
PY - 2020/6/1
Y1 - 2020/6/1
N2 - Reactivation of human herpesvirus (HHV)-6B is relatively common after allogeneic hematopoietic stem cell transplantation (HSCT) and HHV-6B diseases may consequently develop. Among them, HHV-6B encephalitis is a serious and often fatal complication. The aim of these clinical practice recommendations is to provide diagnostic and therapeutic guidance for HHV-6B encephalitis after allogeneic HSCT. In this evidence-based review, we critically evaluated data from the published literature. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology was used to assist in generating recommendations. We have summarized the findings that contribute to decision-making and we have provided our recommendations. In cases where rigorous clinical data are unavailable, recommendations have been developed in discussions with physicians who have relevant expertize.
AB - Reactivation of human herpesvirus (HHV)-6B is relatively common after allogeneic hematopoietic stem cell transplantation (HSCT) and HHV-6B diseases may consequently develop. Among them, HHV-6B encephalitis is a serious and often fatal complication. The aim of these clinical practice recommendations is to provide diagnostic and therapeutic guidance for HHV-6B encephalitis after allogeneic HSCT. In this evidence-based review, we critically evaluated data from the published literature. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology was used to assist in generating recommendations. We have summarized the findings that contribute to decision-making and we have provided our recommendations. In cases where rigorous clinical data are unavailable, recommendations have been developed in discussions with physicians who have relevant expertize.
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U2 - 10.1038/s41409-019-0752-5
DO - 10.1038/s41409-019-0752-5
M3 - Review article
C2 - 31745253
AN - SCOPUS:85075395981
SN - 0268-3369
VL - 55
SP - 1004
EP - 1013
JO - Bone Marrow Transplantation
JF - Bone Marrow Transplantation
IS - 6
ER -
