Cognitive function is associated with home discharge in subacute stroke patients: a retrospective cohort study

Daisuke Ito, Michiyuki Kawakami, Ryota Ishii, Masahiro Tsujikawa, Kaoru Honaga, Kunitsugu Kondo, Tetsuya Tsuji

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1 Citation (Scopus)


Aim: To investigate the cognitive function and its relation to the home discharge of patients following subacute stroke. Methods: This retrospective cohort study included 1,229 convalescent patients experiencing their first subacute stroke. We determined discharge destination and demographic and clinical information. We recorded the following measurement scores: Mini-Mental State Examination (MMSE) score, Stroke Impairment Assessment Set score, grip strength, and Functional Independence Measure (FIM). We performed a multivariable logistic regression analysis with the forced-entry method to identify factors related to home discharge. Results: Of the 1,229 participants (mean age: 68.7 ± 13.5 years), 501 (40.8%), 735 (59.8%), and 1,011 (82.3%) were female, had cerebral infarction, and were home discharged, respectively. Multivariable logistic regression analysis revealed that age (odds ratio [OR], 0.93; 95% confidence interval [CI], 0.91 – 0.96; P < 0.001), duration from stroke onset to admission (OR, 0.98; 95% CI, 0.96 – 0.99; P = 0.003), living situation (OR, 4.40; 95% CI, 2.69 – 7.20; P < 0.001), MMSE score at admission (OR, 1.05; 95% CI, 1.00 – 1.09; P = 0.035), FIM motor score at admission (OR, 1.04; 95% CI, 1.01 – 1.06; P = 0.001), and FIM cognitive score at admission (OR, 1.08; 95% CI, 1.04 – 1.13; P < 0.001) were significantly associated with home discharge. Conclusions: MMSE at admission is significantly associated with home discharge in patients with subacute stroke.

Original languageEnglish
Article number219
JournalBMC Neurology
Issue number1
Publication statusPublished - 2022 Dec


  • Cognitive function
  • Cognitive impairment
  • Discharge destination
  • Retrospective cohort study
  • Stroke

ASJC Scopus subject areas

  • Clinical Neurology


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