Community-acquired pneumonia caused by macrolide-resistant mycoplasma pneumoniae in adults

Shigeo Hanada; Miyuki Morozumi; Yui Takahashi; Sayaka Mochizuki; Toshitaka Sato; Shinko Suzuki; Hironori Uruga; Hisashi Takaya; Atsushi Miyamoto; Nasa Morokawa; Kimiko Ubukata; Kazuma Kishi

doi:10.2169/internalmedicine.53.1418

Community-acquired pneumonia caused by macrolide-resistant mycoplasma pneumoniae in adults

Shigeo Hanada, Miyuki Morozumi, Yui Takahashi, Sayaka Mochizuki, Toshitaka Sato, Shinko Suzuki, Hironori Uruga, Hisashi Takaya, Atsushi Miyamoto, Nasa Morokawa, Kimiko Ubukata, Kazuma Kishi

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

We herein describe a case of community-acquired pneumonia caused by macrolide-resistant Mycoplasma pneumoniae (MRMP) in an adult who responded poorly to macrolide antibiotics, progressively deteriorated to acute respiratory failure and then responded effectively to a fluoroquinolone. In a series of 14 patients with M. pneumoniae pneumonia, 11 were infected with MRMP. In seven of the eight cases of MRMP initially treated with macrolides, the patients did not improve, and a marked improvement was observed only after the antibiotic regimen was modified to include fluoroquinolones or tetracyclines. Nationwide surveillance should provide important information regarding the prevalence and empirical treatment of MRMP infection in adults.

Original language	English
Pages (from-to)	1675-1678
Number of pages	4
Journal	Internal Medicine
Volume	53
Issue number	15
DOIs	https://doi.org/10.2169/internalmedicine.53.1418
Publication status	Published - 2014
Externally published	Yes

Keywords

Community-acquired pneumonia
Macrolide
Mycoplasma pneumoniae

ASJC Scopus subject areas

Internal Medicine

Access to Document

10.2169/internalmedicine.53.1418

Cite this

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title = "Community-acquired pneumonia caused by macrolide-resistant mycoplasma pneumoniae in adults",

abstract = "We herein describe a case of community-acquired pneumonia caused by macrolide-resistant Mycoplasma pneumoniae (MRMP) in an adult who responded poorly to macrolide antibiotics, progressively deteriorated to acute respiratory failure and then responded effectively to a fluoroquinolone. In a series of 14 patients with M. pneumoniae pneumonia, 11 were infected with MRMP. In seven of the eight cases of MRMP initially treated with macrolides, the patients did not improve, and a marked improvement was observed only after the antibiotic regimen was modified to include fluoroquinolones or tetracyclines. Nationwide surveillance should provide important information regarding the prevalence and empirical treatment of MRMP infection in adults.",

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T1 - Community-acquired pneumonia caused by macrolide-resistant mycoplasma pneumoniae in adults

AU - Hanada, Shigeo

AU - Morozumi, Miyuki

AU - Takahashi, Yui

AU - Mochizuki, Sayaka

AU - Sato, Toshitaka

AU - Suzuki, Shinko

AU - Uruga, Hironori

AU - Takaya, Hisashi

AU - Miyamoto, Atsushi

AU - Morokawa, Nasa

AU - Ubukata, Kimiko

AU - Kishi, Kazuma

PY - 2014

Y1 - 2014

N2 - We herein describe a case of community-acquired pneumonia caused by macrolide-resistant Mycoplasma pneumoniae (MRMP) in an adult who responded poorly to macrolide antibiotics, progressively deteriorated to acute respiratory failure and then responded effectively to a fluoroquinolone. In a series of 14 patients with M. pneumoniae pneumonia, 11 were infected with MRMP. In seven of the eight cases of MRMP initially treated with macrolides, the patients did not improve, and a marked improvement was observed only after the antibiotic regimen was modified to include fluoroquinolones or tetracyclines. Nationwide surveillance should provide important information regarding the prevalence and empirical treatment of MRMP infection in adults.

AB - We herein describe a case of community-acquired pneumonia caused by macrolide-resistant Mycoplasma pneumoniae (MRMP) in an adult who responded poorly to macrolide antibiotics, progressively deteriorated to acute respiratory failure and then responded effectively to a fluoroquinolone. In a series of 14 patients with M. pneumoniae pneumonia, 11 were infected with MRMP. In seven of the eight cases of MRMP initially treated with macrolides, the patients did not improve, and a marked improvement was observed only after the antibiotic regimen was modified to include fluoroquinolones or tetracyclines. Nationwide surveillance should provide important information regarding the prevalence and empirical treatment of MRMP infection in adults.

KW - Community-acquired pneumonia

KW - Macrolide

KW - Mycoplasma pneumoniae

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Community-acquired pneumonia caused by macrolide-resistant mycoplasma pneumoniae in adults

Abstract

Keywords

ASJC Scopus subject areas

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