Community-acquired pneumonia caused by macrolide-resistant mycoplasma pneumoniae in adults

Shigeo Hanada, Miyuki Morozumi, Yui Takahashi, Sayaka Mochizuki, Toshitaka Sato, Shinko Suzuki, Hironori Uruga, Hisashi Takaya, Atsushi Miyamoto, Nasa Morokawa, Kimiko Ubukata, Kazuma Kishi

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


We herein describe a case of community-acquired pneumonia caused by macrolide-resistant Mycoplasma pneumoniae (MRMP) in an adult who responded poorly to macrolide antibiotics, progressively deteriorated to acute respiratory failure and then responded effectively to a fluoroquinolone. In a series of 14 patients with M. pneumoniae pneumonia, 11 were infected with MRMP. In seven of the eight cases of MRMP initially treated with macrolides, the patients did not improve, and a marked improvement was observed only after the antibiotic regimen was modified to include fluoroquinolones or tetracyclines. Nationwide surveillance should provide important information regarding the prevalence and empirical treatment of MRMP infection in adults.

Original languageEnglish
Pages (from-to)1675-1678
Number of pages4
JournalInternal Medicine
Issue number15
Publication statusPublished - 2014
Externally publishedYes


  • Community-acquired pneumonia
  • Macrolide
  • Mycoplasma pneumoniae

ASJC Scopus subject areas

  • Internal Medicine


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