TY - GEN
T1 - Comparison of atheromatous tissue ablation between CO laser and excimer laser irradiations
AU - Arai, T.
AU - Nakagawa, M.
AU - Kikuchi, M.
AU - Mizuno, K.
AU - Miyamoto, A.
AU - Okamoto, Y.
AU - Satomura, K.
AU - Shibuya, T.
AU - Arakawa, K.
AU - Isojima, K.
AU - Kurita, A.
AU - Nakamura, H.
AU - Utsumi, A.
AU - Akai, Y.
AU - Katoh, M.
AU - Takeuchi, K.
PY - 1989
Y1 - 1989
N2 - UV (XeCl, XeF excimer) and IR (CO, Er:YAG) lasers are of interest for laser angioplasty owing to their restricted light penetration in living tissue, which prevents vascular perforation. The authors investigated the quantitative ablation rate of vascular tissue, both normal and diseased, by IR (CO) and UV (XeCl, XeF) lasers to determine the optimum laser wavelength for which selective ablation is achieved. All experiments were done in vitro. The results show that CO laser radiation preferentially ablates the yellow atheroma with an affinity factor of 1.8. This affinity factor can be attributed to the low melting (and/or vaporizing) point of fatty materials following thermal ablation by the CO laser. However, XeF laser radiation exhibits an inverse affinity (affinity factor of 0.6). A normal layer of the vascular wall contains more proteins than yellow plaque, so that the absorption of UV lasers in the normal vascular wall may be greater than in the plaque.
AB - UV (XeCl, XeF excimer) and IR (CO, Er:YAG) lasers are of interest for laser angioplasty owing to their restricted light penetration in living tissue, which prevents vascular perforation. The authors investigated the quantitative ablation rate of vascular tissue, both normal and diseased, by IR (CO) and UV (XeCl, XeF) lasers to determine the optimum laser wavelength for which selective ablation is achieved. All experiments were done in vitro. The results show that CO laser radiation preferentially ablates the yellow atheroma with an affinity factor of 1.8. This affinity factor can be attributed to the low melting (and/or vaporizing) point of fatty materials following thermal ablation by the CO laser. However, XeF laser radiation exhibits an inverse affinity (affinity factor of 0.6). A normal layer of the vascular wall contains more proteins than yellow plaque, so that the absorption of UV lasers in the normal vascular wall may be greater than in the plaque.
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M3 - Conference contribution
AN - SCOPUS:0024886761
SN - 1557520860
T3 - CONFERENCE ON LASERS AND ELECTRO-0PTICS
SP - 48
EP - 49
BT - CONFERENCE ON LASERS AND ELECTRO-0PTICS
A2 - Anon, null
PB - Publ by IEEE
T2 - Summaries of Papers Presented at the Conference on Lasers and Electro-Optics
Y2 - 24 April 1989 through 28 April 1989
ER -