Comparison of LASIK with the OPDCAT or OATz algorithm using the NIDEK EC-5000CXII excimer laser

Yoshiko Hori-Komai, Ikuko Toda, Takahiro Yamamoto, Kazuo Tsubota

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


PURPOSE: To compare refractive outcomes, higher order aberrations, visual quality, and patient satisfaction between aspheric and whole-eye wavefront aspheric LASIK algorithms. METHODS: Two hundred seventy-four eyes of 152 patients undergoing LASIK for myopia and myopic astigmatism were divided into two groups: eyes that underwent treatment using either the OPD-guided customized aspheric treatment (OPDCAT) or optimized aspheric treatment zone (OATz). Both groups were subdivided into two groups based on preoperative manifest refraction spherical equivalent (MRSE) <-6.00 diopters (D) and eyes with MRSE ≥-6.00 D. Both groups were additionally subdivided into eyes with preoperative ocular higher order aberrations <0.40 μm and eyes with higher order aberrations ≥0.40 μm. A P value <.05 was considered statistically significant. RESULTS: At 3 months postoperatively, 88.3% (242/274) of eyes were available for follow-up. Postoperatively, 91.4% of eyes in the OPDCAT group and 90.6% of eyes in the OATz group were within 0.50 D. No difference in refractive outcomes and patient satisfaction among groups or subgroups was noted (P>.05). A significantly less change in asphericity (less oblate) was noted for the OPDCAT group (0.31±0.30) compared with the OATz group (0.51±0.35) (P<.05). A lower induction of aberrations in the OPDCAT group compared with the OATz group was noted (P<.05). Mesopic contrast sensitivity was significantly higher for the OPDCAT groups and subgroups (P<.05). CONCLUSIONS: Refractive outcomes between groups or subgroups were equivalent. A significantly lower induction of higher order aberrations and less change in asphericity in the OPDCAT group was noted. The OPDCAT algorithm was more likely to maintain mesopic contrast sensitivity.

Original languageEnglish
Pages (from-to)411-422
Number of pages12
JournalJournal of Refractive Surgery
Issue number6
Publication statusPublished - 2010
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology


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