Complement component 9 deficiency is not a susceptibility factor for SLE

S. Kanemitsu, K. Ihara, R. Kira, Y. Kaku, K. Sakai, K. Tsuzaka, T. Takeuchi, T. Hara

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Almost all complement component 9 (C9) deficiency in Japan shows Arg95Stop mutation of C9 gene. Therefore, we studied the prevalence of Arg95Stop mutation of C9 gene among 78 patients with SLE to elucidate the assocation of SLE and C9 deficiency. The Arg95Stop carrier frequency showed no significant difference between SLE patients and controls. Thus, C9 deficiency is not implicated in SLE susceptibility.

Original languageEnglish
Pages (from-to)456-457
Number of pages2
Issue number6
Publication statusPublished - 2000
Externally publishedYes


  • Collagen disease
  • Complement deficiency
  • Meningococcal meningitis
  • Nonsense mutation

ASJC Scopus subject areas

  • Rheumatology


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