Complement component 9 deficiency is not a susceptibility factor for SLE

S. Kanemitsu; K. Ihara; R. Kira; Y. Kaku; K. Sakai; K. Tsuzaka; T. Takeuchi; T. Hara

doi:10.1191/096120300678828523

Complement component 9 deficiency is not a susceptibility factor for SLE

S. Kanemitsu, K. Ihara, R. Kira, Y. Kaku, K. Sakai, K. Tsuzaka, T. Takeuchi, T. Hara

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Almost all complement component 9 (C9) deficiency in Japan shows Arg95Stop mutation of C9 gene. Therefore, we studied the prevalence of Arg95Stop mutation of C9 gene among 78 patients with SLE to elucidate the assocation of SLE and C9 deficiency. The Arg95Stop carrier frequency showed no significant difference between SLE patients and controls. Thus, C9 deficiency is not implicated in SLE susceptibility.

Original language	English
Pages (from-to)	456-457
Number of pages	2
Journal	Lupus
Volume	9
Issue number	6
DOIs	https://doi.org/10.1191/096120300678828523
Publication status	Published - 2000
Externally published	Yes

Keywords

Collagen disease
Complement deficiency
Meningococcal meningitis
Nonsense mutation

ASJC Scopus subject areas

Rheumatology

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10.1191/096120300678828523

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title = "Complement component 9 deficiency is not a susceptibility factor for SLE",

abstract = "Almost all complement component 9 (C9) deficiency in Japan shows Arg95Stop mutation of C9 gene. Therefore, we studied the prevalence of Arg95Stop mutation of C9 gene among 78 patients with SLE to elucidate the assocation of SLE and C9 deficiency. The Arg95Stop carrier frequency showed no significant difference between SLE patients and controls. Thus, C9 deficiency is not implicated in SLE susceptibility.",

keywords = "Collagen disease, Complement deficiency, Meningococcal meningitis, Nonsense mutation",

author = "S. Kanemitsu and K. Ihara and R. Kira and Y. Kaku and K. Sakai and K. Tsuzaka and T. Takeuchi and T. Hara",

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T1 - Complement component 9 deficiency is not a susceptibility factor for SLE

AU - Kanemitsu, S.

AU - Ihara, K.

AU - Kira, R.

AU - Kaku, Y.

AU - Sakai, K.

AU - Tsuzaka, K.

AU - Takeuchi, T.

AU - Hara, T.

PY - 2000

Y1 - 2000

N2 - Almost all complement component 9 (C9) deficiency in Japan shows Arg95Stop mutation of C9 gene. Therefore, we studied the prevalence of Arg95Stop mutation of C9 gene among 78 patients with SLE to elucidate the assocation of SLE and C9 deficiency. The Arg95Stop carrier frequency showed no significant difference between SLE patients and controls. Thus, C9 deficiency is not implicated in SLE susceptibility.

AB - Almost all complement component 9 (C9) deficiency in Japan shows Arg95Stop mutation of C9 gene. Therefore, we studied the prevalence of Arg95Stop mutation of C9 gene among 78 patients with SLE to elucidate the assocation of SLE and C9 deficiency. The Arg95Stop carrier frequency showed no significant difference between SLE patients and controls. Thus, C9 deficiency is not implicated in SLE susceptibility.

KW - Collagen disease

KW - Complement deficiency

KW - Meningococcal meningitis

KW - Nonsense mutation

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VL - 9

SP - 456

EP - 457

JO - Lupus

JF - Lupus

IS - 6

ER -

Complement component 9 deficiency is not a susceptibility factor for SLE

Abstract

Keywords

ASJC Scopus subject areas

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