TY - JOUR
T1 - Constituents of the Seed of Malva verticillata
T2 - VI: 1) Characterization and Immunological Activities of a Novel Acidic Polysaccharide
AU - Yamada, Haruki
AU - Gonda, Ryoko
AU - Tomoda, Masashi
AU - Kanari, Mieko
AU - Shimizu, Noriko
PY - 1990
Y1 - 1990
N2 - A novel acidic polysaccharide, designated as MVS-VI, was isolated from the seeds of Malva verticillata L. It was homogeneous on electrophoresis and gel chromatography, and its molecular mass was estimated to be 26000. It is composed of L-arabinose: D-xylose: D-galactose: D-glucose: L-rhamnose: D-galacturonic acid in the molar ratio of 30:15:20:3:2:10, in addition to small amounts of peptide moiety. Methylation analysis, carbon-13 nuclear magnetic resonance and periodate oxidation studies indicated its structural features to have mainly acidic α-arabino-3,6-β-galactan type structural units. MVS-VI showed significant reticuloendothelial system-potentiating activity in a carbon clearance test, and it possesses remarkable anti-complementary activity.
AB - A novel acidic polysaccharide, designated as MVS-VI, was isolated from the seeds of Malva verticillata L. It was homogeneous on electrophoresis and gel chromatography, and its molecular mass was estimated to be 26000. It is composed of L-arabinose: D-xylose: D-galactose: D-glucose: L-rhamnose: D-galacturonic acid in the molar ratio of 30:15:20:3:2:10, in addition to small amounts of peptide moiety. Methylation analysis, carbon-13 nuclear magnetic resonance and periodate oxidation studies indicated its structural features to have mainly acidic α-arabino-3,6-β-galactan type structural units. MVS-VI showed significant reticuloendothelial system-potentiating activity in a carbon clearance test, and it possesses remarkable anti-complementary activity.
KW - MVS-VI
KW - Malva verticillata
KW - acidic arabinogalactan
KW - anti-complementary activity
KW - immunological activity
KW - polysaccharide structure
KW - reticuloendothelial system
KW - seed
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U2 - 10.1248/cpb.38.2771
DO - 10.1248/cpb.38.2771
M3 - Article
C2 - 2076561
AN - SCOPUS:0025115922
SN - 0009-2363
VL - 38
SP - 2771
EP - 2774
JO - Chemical and Pharmaceutical Bulletin
JF - Chemical and Pharmaceutical Bulletin
IS - 10
ER -