Abstract
A novel acidic polysaccharide, designated as MVS-VI, was isolated from the seeds of Malva verticillata L. It was homogeneous on electrophoresis and gel chromatography, and its molecular mass was estimated to be 26000. It is composed of L-arabinose: D-xylose: D-galactose: D-glucose: L-rhamnose: D-galacturonic acid in the molar ratio of 30:15:20:3:2:10, in addition to small amounts of peptide moiety. Methylation analysis, carbon-13 nuclear magnetic resonance and periodate oxidation studies indicated its structural features to have mainly acidic α-arabino-3,6-β-galactan type structural units. MVS-VI showed significant reticuloendothelial system-potentiating activity in a carbon clearance test, and it possesses remarkable anti-complementary activity.
| Original language | English |
|---|---|
| Pages (from-to) | 2771-2774 |
| Number of pages | 4 |
| Journal | Chemical and Pharmaceutical Bulletin |
| Volume | 38 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 1990 |
Keywords
- MVS-VI
- Malva verticillata
- acidic arabinogalactan
- anti-complementary activity
- immunological activity
- polysaccharide structure
- reticuloendothelial system
- seed
ASJC Scopus subject areas
- General Chemistry
- Drug Discovery
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