Crystal structure of (±)-(7RS,8SR)-7-methyl-1,4-dioxaspiro[4.5]decane-7,8-diol

Takeshi Oishi, Hiroaki Yamamoto, Tomoya Sugai, Keisuke Fukaya, Yu Yamaguchi, Ami Watanabe, Takaaki Sato, Noritaka Chida

Research output: Contribution to journalArticlepeer-review


In the title compound, C9H16O4, the five-membered dioxolane ring adopts a twist conformation; two adjacent C atoms deviate alternately from the mean plane of other atoms by -0.297(4) and 0.288(4)Å. The spiro-fused cyclohexane ring shows a chair form. The hydroxy group substituted in an axial position makes an intramolecular O - H⋯O hydrogen bond with one of the O atoms in the cyclic ether, forming an S(6) ring motif. In the crystal, the O - H⋯O hydrogen bond involving the equatorial hydroxy group connects the molecules into a zigzag chain with a C(5) motif running along the c axis.

Original languageEnglish
Pages (from-to)1181-1184
Number of pages4
JournalActa Crystallographica Section E: Crystallographic Communications
Publication statusPublished - 2015


  • crystal structure
  • cyclohexane
  • hydrogen bonds
  • hydroxy groups
  • paclitaxel

ASJC Scopus subject areas

  • General Chemistry
  • General Materials Science
  • Condensed Matter Physics


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