Current status of alcoholic hepatocellular carcinoma in Japan -nation-wide survey in 2014

Yoshinori Horie; Masahiro Kikuchi; Hirotoshi Ebinuma; Syunsuke Shiba; Nobuhito Taniki; Po Sung Chu; Nobuhiro Nakamoto; Takanori Kanai

doi:10.2957/kanzo.57.538

Current status of alcoholic hepatocellular carcinoma in Japan -nation-wide survey in 2014

Yoshinori Horie, Masahiro Kikuchi, Hirotoshi Ebinuma, Syunsuke Shiba, Nobuhito Taniki, Po Sung Chu, Nobuhiro Nakamoto, Takanori Kanai

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We carried out a nation-wide survey of hepatocellular carcinoma (HCC) by asking major hospitals in Japan to provide information on the number of patients with HCC diagnosed or treated in 2014 along with information related to etiology including alcohol history. In 7047 HCC cases, etiological agents were as follows: HBV 13.9%, HCV 54.8%, and alcoholic HCC (ALD-HCC) 13.9%. Of HCC cases, 25.8% took ethanol over 60 g/day. Mean age of 333 ALD-HCC patients was 69.8y. Elder patients had lower Child-Pugh score than younger patients. The prevalence of ALD-HCC has been increasing in Japan. Age was identified as risk factors for development of ALD-HCC. Reduction of alcohol intake is the most fundamental measure to prevent ALD-HCC. However, early diagnosis of HCC by image procedures in heavy drinkers is an important measure for a decrease in the cause of death from HCC.

Original language	English
Pages (from-to)	538-547
Number of pages	10
Journal	Acta Hepatologica Japonica
Volume	57
Issue number	10
DOIs	https://doi.org/10.2957/kanzo.57.538
Publication status	Published - 2016

Keywords

Age
Child-pugh score
Fundamental law on measures to prevent damage to health due to alcohol
Hepatocellular carcinoma
Liver cirrhosis

ASJC Scopus subject areas

Hepatology

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10.2957/kanzo.57.538

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title = "Current status of alcoholic hepatocellular carcinoma in Japan -nation-wide survey in 2014",

abstract = "We carried out a nation-wide survey of hepatocellular carcinoma (HCC) by asking major hospitals in Japan to provide information on the number of patients with HCC diagnosed or treated in 2014 along with information related to etiology including alcohol history. In 7047 HCC cases, etiological agents were as follows: HBV 13.9%, HCV 54.8%, and alcoholic HCC (ALD-HCC) 13.9%. Of HCC cases, 25.8% took ethanol over 60 g/day. Mean age of 333 ALD-HCC patients was 69.8y. Elder patients had lower Child-Pugh score than younger patients. The prevalence of ALD-HCC has been increasing in Japan. Age was identified as risk factors for development of ALD-HCC. Reduction of alcohol intake is the most fundamental measure to prevent ALD-HCC. However, early diagnosis of HCC by image procedures in heavy drinkers is an important measure for a decrease in the cause of death from HCC.",

keywords = "Age, Child-pugh score, Fundamental law on measures to prevent damage to health due to alcohol, Hepatocellular carcinoma, Liver cirrhosis",

author = "Yoshinori Horie and Masahiro Kikuchi and Hirotoshi Ebinuma and Syunsuke Shiba and Nobuhito Taniki and Chu, {Po Sung} and Nobuhiro Nakamoto and Takanori Kanai",

note = "Publisher Copyright: {\textcopyright} 2016 The Japan Society of Hepatology.",

year = "2016",

doi = "10.2957/kanzo.57.538",

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AU - Horie, Yoshinori

AU - Kikuchi, Masahiro

AU - Ebinuma, Hirotoshi

AU - Shiba, Syunsuke

AU - Taniki, Nobuhito

AU - Chu, Po Sung

AU - Nakamoto, Nobuhiro

AU - Kanai, Takanori

PY - 2016

Y1 - 2016

N2 - We carried out a nation-wide survey of hepatocellular carcinoma (HCC) by asking major hospitals in Japan to provide information on the number of patients with HCC diagnosed or treated in 2014 along with information related to etiology including alcohol history. In 7047 HCC cases, etiological agents were as follows: HBV 13.9%, HCV 54.8%, and alcoholic HCC (ALD-HCC) 13.9%. Of HCC cases, 25.8% took ethanol over 60 g/day. Mean age of 333 ALD-HCC patients was 69.8y. Elder patients had lower Child-Pugh score than younger patients. The prevalence of ALD-HCC has been increasing in Japan. Age was identified as risk factors for development of ALD-HCC. Reduction of alcohol intake is the most fundamental measure to prevent ALD-HCC. However, early diagnosis of HCC by image procedures in heavy drinkers is an important measure for a decrease in the cause of death from HCC.

AB - We carried out a nation-wide survey of hepatocellular carcinoma (HCC) by asking major hospitals in Japan to provide information on the number of patients with HCC diagnosed or treated in 2014 along with information related to etiology including alcohol history. In 7047 HCC cases, etiological agents were as follows: HBV 13.9%, HCV 54.8%, and alcoholic HCC (ALD-HCC) 13.9%. Of HCC cases, 25.8% took ethanol over 60 g/day. Mean age of 333 ALD-HCC patients was 69.8y. Elder patients had lower Child-Pugh score than younger patients. The prevalence of ALD-HCC has been increasing in Japan. Age was identified as risk factors for development of ALD-HCC. Reduction of alcohol intake is the most fundamental measure to prevent ALD-HCC. However, early diagnosis of HCC by image procedures in heavy drinkers is an important measure for a decrease in the cause of death from HCC.

KW - Age

KW - Child-pugh score

KW - Fundamental law on measures to prevent damage to health due to alcohol

KW - Hepatocellular carcinoma

KW - Liver cirrhosis

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Current status of alcoholic hepatocellular carcinoma in Japan -nation-wide survey in 2014

Abstract

Keywords

ASJC Scopus subject areas

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