TY - JOUR
T1 - Deep learning in diabetic foot ulcers detection
T2 - A comprehensive evaluation
AU - Yap, Moi Hoon
AU - Hachiuma, Ryo
AU - Alavi, Azadeh
AU - Brüngel, Raphael
AU - Cassidy, Bill
AU - Goyal, Manu
AU - Zhu, Hongtao
AU - Rückert, Johannes
AU - Olshansky, Moshe
AU - Huang, Xiao
AU - Saito, Hideo
AU - Hassanpour, Saeed
AU - Friedrich, Christoph M.
AU - Ascher, David B.
AU - Song, Anping
AU - Kajita, Hiroki
AU - Gillespie, David
AU - Reeves, Neil D.
AU - Pappachan, Joseph M.
AU - O'Shea, Claire
AU - Frank, Eibe
N1 - Funding Information:
We gratefully acknowledge the support of NVIDIA Corporation for the use of GPUs during the challenge and for sponsoring our event. A.A., D.B.A. and M.O. were supported by the National Health and Medical Research Council [ GNT1174405 ] and the Victorian Government 's OIS Program. The work of R.B. was partially funded by a PhD grant from the University of Applied Sciences and Arts Dortmund , 44227 Dortmund, Germany.
Funding Information:
We gratefully acknowledge the support of NVIDIA Corporation for the use of GPUs during the challenge and for sponsoring our event. A.A. D.B.A. and M.O. were supported by the National Health and Medical Research Council [GNT1174405] and the Victorian Government's OIS Program. The work of R.B. was partially funded by a PhD grant from the University of Applied Sciences and Arts Dortmund, 44227 Dortmund, Germany.
Publisher Copyright:
© 2021 The Authors
PY - 2021/8
Y1 - 2021/8
N2 - There has been a substantial amount of research involving computer methods and technology for the detection and recognition of diabetic foot ulcers (DFUs), but there is a lack of systematic comparisons of state-of-the-art deep learning object detection frameworks applied to this problem. DFUC2020 provided participants with a comprehensive dataset consisting of 2,000 images for training and 2,000 images for testing. This paper summarizes the results of DFUC2020 by comparing the deep learning-based algorithms proposed by the winning teams: Faster R–CNN, three variants of Faster R–CNN and an ensemble method; YOLOv3; YOLOv5; EfficientDet; and a new Cascade Attention Network. For each deep learning method, we provide a detailed description of model architecture, parameter settings for training and additional stages including pre-processing, data augmentation and post-processing. We provide a comprehensive evaluation for each method. All the methods required a data augmentation stage to increase the number of images available for training and a post-processing stage to remove false positives. The best performance was obtained from Deformable Convolution, a variant of Faster R–CNN, with a mean average precision (mAP) of 0.6940 and an F1-Score of 0.7434. Finally, we demonstrate that the ensemble method based on different deep learning methods can enhance the F1-Score but not the mAP.
AB - There has been a substantial amount of research involving computer methods and technology for the detection and recognition of diabetic foot ulcers (DFUs), but there is a lack of systematic comparisons of state-of-the-art deep learning object detection frameworks applied to this problem. DFUC2020 provided participants with a comprehensive dataset consisting of 2,000 images for training and 2,000 images for testing. This paper summarizes the results of DFUC2020 by comparing the deep learning-based algorithms proposed by the winning teams: Faster R–CNN, three variants of Faster R–CNN and an ensemble method; YOLOv3; YOLOv5; EfficientDet; and a new Cascade Attention Network. For each deep learning method, we provide a detailed description of model architecture, parameter settings for training and additional stages including pre-processing, data augmentation and post-processing. We provide a comprehensive evaluation for each method. All the methods required a data augmentation stage to increase the number of images available for training and a post-processing stage to remove false positives. The best performance was obtained from Deformable Convolution, a variant of Faster R–CNN, with a mean average precision (mAP) of 0.6940 and an F1-Score of 0.7434. Finally, we demonstrate that the ensemble method based on different deep learning methods can enhance the F1-Score but not the mAP.
KW - DFUC2020
KW - Deep learning
KW - Diabetic foot ulcers
KW - Machine learning
KW - Object detection
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U2 - 10.1016/j.compbiomed.2021.104596
DO - 10.1016/j.compbiomed.2021.104596
M3 - Article
C2 - 34247133
AN - SCOPUS:85109461472
SN - 0010-4825
VL - 135
JO - Computers in Biology and Medicine
JF - Computers in Biology and Medicine
M1 - 104596
ER -