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Deep learning in diabetic foot ulcers detection: A comprehensive evaluation

  • Moi Hoon Yap
  • , Ryo Hachiuma
  • , Azadeh Alavi
  • , Raphael Brüngel
  • , Bill Cassidy
  • , Manu Goyal
  • , Hongtao Zhu
  • , Johannes Rückert
  • , Moshe Olshansky
  • , Xiao Huang
  • , Hideo Saito
  • , Saeed Hassanpour
  • , Christoph M. Friedrich
  • , David B. Ascher
  • , Anping Song
  • , Hiroki Kajita
  • , David Gillespie
  • , Neil D. Reeves
  • , Joseph M. Pappachan
  • , Claire O'Shea
  • Eibe Frank

Research output: Contribution to journalArticlepeer-review

Abstract

There has been a substantial amount of research involving computer methods and technology for the detection and recognition of diabetic foot ulcers (DFUs), but there is a lack of systematic comparisons of state-of-the-art deep learning object detection frameworks applied to this problem. DFUC2020 provided participants with a comprehensive dataset consisting of 2,000 images for training and 2,000 images for testing. This paper summarizes the results of DFUC2020 by comparing the deep learning-based algorithms proposed by the winning teams: Faster R–CNN, three variants of Faster R–CNN and an ensemble method; YOLOv3; YOLOv5; EfficientDet; and a new Cascade Attention Network. For each deep learning method, we provide a detailed description of model architecture, parameter settings for training and additional stages including pre-processing, data augmentation and post-processing. We provide a comprehensive evaluation for each method. All the methods required a data augmentation stage to increase the number of images available for training and a post-processing stage to remove false positives. The best performance was obtained from Deformable Convolution, a variant of Faster R–CNN, with a mean average precision (mAP) of 0.6940 and an F1-Score of 0.7434. Finally, we demonstrate that the ensemble method based on different deep learning methods can enhance the F1-Score but not the mAP.

Original languageEnglish
Article number104596
JournalComputers in Biology and Medicine
Volume135
DOIs
Publication statusPublished - 2021 Aug

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • DFUC2020
  • Deep learning
  • Diabetic foot ulcers
  • Machine learning
  • Object detection

ASJC Scopus subject areas

  • Health Informatics
  • Computer Science Applications

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