Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application

Yoko Takano; Kenjiro Hanaoka; Kazuhito Shimamoto; Ryo Miyamoto; Toru Komatsu; Tasuku Ueno; Takuya Terai; Hideo Kimura; Tetsuo Nagano; Yasuteru Urano

doi:10.1039/c6cc08372b

Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application

Yoko Takano, Kenjiro Hanaoka, Kazuhito Shimamoto, Ryo Miyamoto, Toru Komatsu, Tasuku Ueno, Takuya Terai, Hideo Kimura, Tetsuo Nagano, Yasuteru Urano

Research output: Contribution to journal › Article › peer-review

65 Citations (Scopus)

Abstract

We report a reversible off/on fluorescent probe for monitoring concentration changes of sulfane sulfur by utilizing the unique ability of sulfane sulfur to bind reversibly to other sulfur atoms and the intramolecular spirocyclization reaction of xanthene dyes. It reversibly visualized sulfane sulfur in living A549 cells and primary-cultured hippocampal astrocytes.

Original language	English
Pages (from-to)	1064-1067
Number of pages	4
Journal	Chemical Communications
Volume	53
Issue number	6
DOIs	https://doi.org/10.1039/c6cc08372b
Publication status	Published - 2017
Externally published	Yes

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Ceramics and Composites
Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
Chemistry(all)
Catalysis

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10.1039/c6cc08372b

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abstract = "We report a reversible off/on fluorescent probe for monitoring concentration changes of sulfane sulfur by utilizing the unique ability of sulfane sulfur to bind reversibly to other sulfur atoms and the intramolecular spirocyclization reaction of xanthene dyes. It reversibly visualized sulfane sulfur in living A549 cells and primary-cultured hippocampal astrocytes.",

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AU - Takano, Yoko

AU - Hanaoka, Kenjiro

AU - Shimamoto, Kazuhito

AU - Miyamoto, Ryo

AU - Komatsu, Toru

AU - Ueno, Tasuku

AU - Terai, Takuya

AU - Kimura, Hideo

AU - Nagano, Tetsuo

AU - Urano, Yasuteru

PY - 2017

Y1 - 2017

N2 - We report a reversible off/on fluorescent probe for monitoring concentration changes of sulfane sulfur by utilizing the unique ability of sulfane sulfur to bind reversibly to other sulfur atoms and the intramolecular spirocyclization reaction of xanthene dyes. It reversibly visualized sulfane sulfur in living A549 cells and primary-cultured hippocampal astrocytes.

AB - We report a reversible off/on fluorescent probe for monitoring concentration changes of sulfane sulfur by utilizing the unique ability of sulfane sulfur to bind reversibly to other sulfur atoms and the intramolecular spirocyclization reaction of xanthene dyes. It reversibly visualized sulfane sulfur in living A549 cells and primary-cultured hippocampal astrocytes.

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DO - 10.1039/c6cc08372b

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JO - Chemical Communications

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ER -

Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application

Abstract

ASJC Scopus subject areas

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