@article{811ead8b9cad463db332c2f2bcf5f0fb,
title = "Development of simple firefly luciferin analogs emitting blue, green, red, and near-infrared biological window light",
abstract = "Simple firefly luciferin analogs emitting blue, green, and red light were developed. The longest emission maximum was observed at 675 nm, which belongs to the NIR biological window (650-900 nm), useful for deep site bioimaging of living animals. The analogs showed a slow rise of emission intensity compared with the rapid emission of natural luciferin. The light emission of the adenylated analogs was strongly enhanced compared with those of analogs themselves.",
keywords = "Biological window, Bioluminescence, Firefly, Luciferin analog, Near-infrared",
author = "Satoshi Iwano and Rika Obata and Chihiro Miura and Masahiro Kiyama and Kazutoshi Hama and Mitsuhiro Nakamura and Yoshiharu Amano and Satoshi Kojima and Takashi Hirano and Shojiro Maki and Haruki Niwa",
note = "Funding Information: The authors are deeply grateful to Dr. Shigeru Nishiyama (Keio University, Yokohama, Japan) for enthusiastic support and critical review. This work was supported by Grants-in-Aid for Exploratory Research (No. 24650633 ) to S.M. from the Ministry of Education, Culture, Sports, Science and Technology , and Adaptable & Seamless Technology Transfer Program through Target-driven R&D (A-Step) (No. AS2321366E ) to S.M. from the Japan Science and Technology Agency .",
year = "2013",
month = may,
day = "13",
doi = "10.1016/j.tet.2013.03.050",
language = "English",
volume = "69",
pages = "3847--3856",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Limited",
number = "19",
}