TY - JOUR
T1 - Disseminated Mycobacterium genavense infection in patient with adult-onset immunodeficiency
AU - Asakura, Takanori
AU - Namkoong, Ho
AU - Sakagami, Takuro
AU - Hasegawa, Naoki
AU - Ohkusu, Kiyofumi
AU - Nakamura, Akira
N1 - Publisher Copyright:
© 2017, Centers for Disease Control and Prevention (CDC). All rights reserved.
PY - 2017/7
Y1 - 2017/7
N2 - We report a case of disseminated Mycobacterium genavense infection resulting from neutralizing anti–interferon-γ autoantibodies in the patient. We identified M. genavense targeting the hsp65 gene in an aspiration specimen of the lymph node. Adult-onset immunodeficiency caused by neutralizing anti–interferon-γ autoantibodies, in addition to HIV infection, can lead to disseminated nontuberculous mycobacterial infection.
AB - We report a case of disseminated Mycobacterium genavense infection resulting from neutralizing anti–interferon-γ autoantibodies in the patient. We identified M. genavense targeting the hsp65 gene in an aspiration specimen of the lymph node. Adult-onset immunodeficiency caused by neutralizing anti–interferon-γ autoantibodies, in addition to HIV infection, can lead to disseminated nontuberculous mycobacterial infection.
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U2 - 10.3201/eid2307.161677
DO - 10.3201/eid2307.161677
M3 - Letter
C2 - 28628454
AN - SCOPUS:85021075002
SN - 1080-6040
VL - 23
SP - 1208
EP - 1210
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 7
ER -