Diversity of clinical isolates of Entamoeba histolytica in Japan

Tomoyoshi Nozaki, Seiki Kobayashi, Tsutomu Takeuchi, Ali Haghighi

Research output: Contribution to journalReview articlepeer-review

29 Citations (Scopus)


In Japan, amebiasis is domestically transmitted by two major populations: male homosexuals and mentally handicapped persons, which is remarkably different from most other developed countries where Entamoeba dispar infection is predominantly observed. Here we briefly summarize epidemiology of amebiasis in Japan. We also review our current understanding of the diversity of Entamoeba histolytica clinical isolates in Japan, based on polymorphic genetic markers, clinical representations, and in vivo virulence, using an animal model.

Original languageEnglish
Pages (from-to)276-278
Number of pages3
JournalArchives of Medical Research
Issue number2
Publication statusPublished - 2006 Feb
Externally publishedYes


  • Amebiasis
  • Epidemiology
  • Heterogeneity
  • Mentally handicapped persons
  • Sexually transmitted disease

ASJC Scopus subject areas

  • General Medicine


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