Abstract
A recent article published in Nature presents intriguing data suggesting that the activation of neuronal nuclear factor-κB (NF-κB) in the mediobasal hypothalamus (MBH) causes systemic aging through reduced secretion of gonadotropin-releasing hormone, an anti-aging hormone. Microglial inflammation in MBH also seems to induce neuronal NF-κB. These results raise the possibility that neuroinflammation orchestrates systemic aging.
| Original language | English |
|---|---|
| Pages (from-to) | 155-156 |
| Number of pages | 2 |
| Journal | Clinical and Experimental Neuroimmunology |
| Volume | 4 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2013 Aug |
ASJC Scopus subject areas
- Neuroscience (miscellaneous)
- Immunology
- Immunology and Microbiology (miscellaneous)
- Clinical Neurology