“Drop-slip” bulk sample flow on fully inkjet-printed microfluidic paper-based analytical device

Terence G. Henares, Kentaro Yamada, Shunsuke Takaki, Koji Suzuki, Daniel Citterio

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)


With “drop-slip” (DS) bulk liquid flow on a fully inkjet-printed microfluidic paper-based analytical device (μPAD), a new method for the rapid transport of sample liquid is presented. The main driving force for DS flow is the slip flow of fluid on wetted porous cellulose acting as a lubricated surface, which is predominantly influenced by the width of the hydrophilic channel and the surface tension of the sample liquid. The application of DS flow is demonstrated by a model colorimetric metal assay (Zn2+, Cu2+, Fe2+) with inkjet-deposited indicators on a μPAD with optimized channel dimensions of 2 mm width and 110 μm height. The presence of bulk liquid on the entire device does not result in any mixing of assay components across adjacent sensing regions connected by microfluidic channels. DS flow is a useful alternative sample liquid transport method for μPADs, allowing to perform multiple fully independent assays with enlarged sample volumes without requiring any significant variation in device design and fabrication.

Original languageEnglish
Pages (from-to)1129-1137
Number of pages9
JournalSensors and Actuators, B: Chemical
Publication statusPublished - 2017


  • Free surface flow
  • Inkjet printing
  • Microfluidic paper-based analytical device

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry


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