Drug discovery assisted by kinetic target guided synthesis

Research output: Contribution to journalArticlepeer-review


One of the modern medicinal chemistry methods is kinetic target-guided synthesis, where fragment molecules are interacted with a target protein and those in close proximity on the protein spontaneously cross - link by forming a covalent bond. The reactions, which is applicable to the kinetic target-guided synthesis proceed in water and are required no additional reagent. Here, several examples of kinetic target - guided synthesis are described.

Original languageEnglish
Pages (from-to)1245-1246
Number of pages2
JournalYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
Issue number12
Publication statusPublished - 2015
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry


Dive into the research topics of 'Drug discovery assisted by kinetic target guided synthesis'. Together they form a unique fingerprint.

Cite this