Abstract
One of the modern medicinal chemistry methods is kinetic target-guided synthesis, where fragment molecules are interacted with a target protein and those in close proximity on the protein spontaneously cross - link by forming a covalent bond. The reactions, which is applicable to the kinetic target-guided synthesis proceed in water and are required no additional reagent. Here, several examples of kinetic target - guided synthesis are described.
| Original language | English |
|---|---|
| Pages (from-to) | 1245-1246 |
| Number of pages | 2 |
| Journal | Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry |
| Volume | 73 |
| Issue number | 12 |
| Publication status | Published - 2015 |
| Externally published | Yes |
ASJC Scopus subject areas
- Organic Chemistry