@inproceedings{accd89c31a69418da1adf0040fb2bc5f,
title = "Dual-Sensing Mechanical Hydrogel Biosensor Composed by Aptamer Recognition and DNA Logic Gates",
abstract = "This paper presents a hydrogel biosensor that can simultaneously sense the co-existence of two substances through mechanical response using aptamer molecular recognition and DNA logic gates. Mechanical response is a preferable property in hydrogel sensors, so we have created a swelling hydrogel biosensor and have also added logical processing abilities to widen the applications of the sensor. We demonstrated the biosensor's ability against two targets, caffeine and theophylline, by measuring the swelling ratio of the hydrogel. We believe that our proposed hydrogel biosensor can be applied to many MEMS and μTAS applications because of its mechanical responsiveness and programmable reactions.",
keywords = "Aptamer, Biosensor, Chemical sensor, DNA nanotechnology, Hydrogel, Logic gates, μTAS",
author = "Satofumi Kato and Masahiro Takinoue and Hiroaki Onoe",
note = "Publisher Copyright: {\textcopyright} 2024 IEEE.; 37th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2024 ; Conference date: 21-01-2024 Through 25-01-2024",
year = "2024",
doi = "10.1109/MEMS58180.2024.10439374",
language = "English",
series = "Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "322--325",
booktitle = "IEEE 37th International Conference on Micro Electro Mechanical Systems, MEMS 2024",
}