Effect of oxygen plasma treatment on non-thrombogenicity of diamond-like carbon films

S. Nagashima, T. Hasebe, A. Kamijo, Y. Yoshimoto, A. Hotta, H. Morita, H. Terada, M. Tanaka, K. Takahashi, T. Suzuki

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)


The non-thrombogenicity of oxygen-plasma-treated DLC films was investigated as surface coatings for medical devices. DLC films were deposited on polycarbonate substrates by a radio frequency plasma enhanced chemical vapor deposition method using acetylene gas. The deposited DLC films were then treated with plasma of oxygen gas at powers of 15 W, 50 W, and 200 W. Wettability was evaluated by water contact angle measurements and the changes in surface chemistry and roughness were examined by X-ray photoelectron spectroscopy and atomic force microscope analysis, respectively. Each oxygen-plasma-treated DLC film exhibited a hydrophilic nature with water contact angles of 11.1°, 17.7° and 36.8°. The non-thrombogenicity of the samples was evaluated through the incubation with platelet-rich plasma isolated from human whole blood. Non-thrombogenic properties dramatically improved for both 15 W- and 50 W-oxygen-plasma-treated DLC films. These results demonstrate that the oxygen plasma treatment at lower powers promotes the non-thrombogenicity of DLC films with highly hydrophilic surfaces.

Original languageEnglish
Pages (from-to)861-865
Number of pages5
JournalDiamond and Related Materials
Issue number7-9
Publication statusPublished - 2010 Jul


  • Biomedical applications
  • Diamond-like carbon
  • Plasma CVD
  • Surface characterization

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • General Chemistry
  • Mechanical Engineering
  • Materials Chemistry
  • Electrical and Electronic Engineering


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