Abstract
Effects of static magnetic fields (SMFs) on development of hypertension were investigated using young male, stroke resistant, spontaneously hypertensive rats (SHRs) beginning at 7 weeks of age. SHRs were randomly assigned to two different exposure groups or an unexposed group. The SHRs in the exposure groups were constantly exposed to two different types of external SMFs of 3.0-10.0 mT or 8.0-25.0 mT for 12 weeks. The SMFs were generated from permanent magnetic plates attached to the rat cage. The blood pressure (BP) of each rat was determined at weekly intervals using indirect tail-cuff method. The SMFs suppressed and retarded the development of hypertension in both exposed groups to a statistically significant extent for several weeks, as compared with an unexposed group. The antipressor effects were related to the extent of reduction in plasma levels of angiotensin II and aldosterone in the SHRs. These results suggest that the SMFs of mT intensities with spatial gradients could be attributable to suppression of early BP elevation via hormonal regulatory system.
| Original language | English |
|---|---|
| Pages (from-to) | 403-412 |
| Number of pages | 10 |
| Journal | Bioelectromagnetics |
| Volume | 24 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2003 Sept |
| Externally published | Yes |
Keywords
- Antihypertensive effects
- DC magnetic fields
- Plasma
- Spontaneous hypertension
ASJC Scopus subject areas
- Biophysics
- Physiology
- Radiology Nuclear Medicine and imaging
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