Egg and sperm recognition systems during fertilization

Noritaka Hirohashi, Noriko Kamei, Hideo Kubo, Hitoshi Sawada, Midori Matsumoto, Motonori Hoshi

Research output: Contribution to journalReview articlepeer-review

66 Citations (Scopus)


Fertilization is a programmed process that has many molecules and sequential events amenable to study. The biochemistry of fertilization has identified cellular and acellular components fundamental to the interactions between sperm and egg. Recent studies highlight the molecular details of the species-specificity of fertilization that involve protein-protein and protein-carbohydrate interactions. Although the diversity of structure and mechanism may imply rapid evolution of fertilization proteins, understanding the structure-function relationships has become important. Here, we introduce the molecules controlling the sperm AR, sperm attachment to, and penetration through, the egg investments.

Original languageEnglish
Pages (from-to)S221-S238
JournalDevelopment Growth and Differentiation
Issue numberSUPPL. 1
Publication statusPublished - 2008 Jun


  • Acrosome reaction
  • Acrosome reaction-inducing substance (ARIS)
  • Bindin
  • Egg coat
  • Fertilization
  • Lysin

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology


Dive into the research topics of 'Egg and sperm recognition systems during fertilization'. Together they form a unique fingerprint.

Cite this