En bloc resection of a large semicircular esophageal cancer by endoscopic submucosal dissection

Mitsuhiro Fujishiro, Naohisa Yahagi, Naomi Kakushima, Shinya Kodashima, Masao Ichinose, Masao Omata

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)


A semicircular esophageal cancer, approximately 7 cm wide, was detected in the middle to lower esophagus of an 81-year-old gentleman during an esophagogastroduodenoscopy. Thorough examinations using chromoendoscopy and endoscopic ultrasonography led to preoperative diagnosis of an intramucosal tumor. With informed consent, the patient underwent endoscopic submucosal dissection (ESD), a novel endoscopic treatment. A successful en bloc resection by ESD was completed without complications. The resected specimen measured 72 mm by 35 mm, and the cancer was contained in an area of 66 mm by 32 mm. Histologic assessment revealed squamous cell carcinoma, microinvasive into the mucosal layer, but without vessel infiltration. Six months after ESD, mild stenosis remained, but dilation was no longer needed, and esophagogastroduodenoscopy with chromoendoscopy and biopsy revealed no residual or recurrent cancer.

Original languageEnglish
Pages (from-to)237-241
Number of pages5
JournalSurgical Laparoscopy, Endoscopy and Percutaneous Techniques
Issue number4
Publication statusPublished - 2006 Aug
Externally publishedYes


  • En bloc resection
  • Endoscopic mucosal resection
  • Endoscopic submucosal dissection
  • Esophageal neoplasm
  • Esophageal stenosis
  • Flex knife

ASJC Scopus subject areas

  • Surgery


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