Enantioselective distribution behavior of (±)-pindolol in a liquid- liquid two-phase system containing optically active diol and boric acid

Yoshihiro Abe; Wang Qing; Tomoko Shoji; Shikie Fukui; Mayumi Suzuki; Takako Kamiyama; Michi Kobayashi; Hideyuki Nishizawa

doi:10.1248/cpb.44.1250

Enantioselective distribution behavior of (±)-pindolol in a liquid- liquid two-phase system containing optically active diol and boric acid

Yoshihiro Abe, Wang Qing, Tomoko Shoji, Shikie Fukui, Mayumi Suzuki, Takako Kamiyama, Michi Kobayashi, Hideyuki Nishizawa

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Enantioselective distribution of (±)-pindolol was observed in a chloroform-boric acid two-phase system in the presence of (1R,2R)-(+)- hydrobenzoin,1,4-di-O-dodecyl L-threitol, (R)-(+)- or (S)-(-)-1,1'-2- binaphthol in the organic phase.

Original language	English
Pages (from-to)	1250-1251
Number of pages	2
Journal	Chemical and Pharmaceutical Bulletin
Volume	44
Issue number	6
DOIs	https://doi.org/10.1248/cpb.44.1250
Publication status	Published - 1996 Jun

Keywords

binaphthol
boric acid
enantioseparation
hydrobenzoin
liquid liquid extraction

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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abstract = "Enantioselective distribution of (±)-pindolol was observed in a chloroform-boric acid two-phase system in the presence of (1R,2R)-(+)- hydrobenzoin,1,4-di-O-dodecyl L-threitol, (R)-(+)- or (S)-(-)-1,1'-2- binaphthol in the organic phase.",

keywords = "binaphthol, boric acid, enantioseparation, hydrobenzoin, liquid liquid extraction",

author = "Yoshihiro Abe and Wang Qing and Tomoko Shoji and Shikie Fukui and Mayumi Suzuki and Takako Kamiyama and Michi Kobayashi and Hideyuki Nishizawa",

year = "1996",

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doi = "10.1248/cpb.44.1250",

language = "English",

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pages = "1250--1251",

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T1 - Enantioselective distribution behavior of (±)-pindolol in a liquid- liquid two-phase system containing optically active diol and boric acid

AU - Abe, Yoshihiro

AU - Qing, Wang

AU - Shoji, Tomoko

AU - Fukui, Shikie

AU - Suzuki, Mayumi

AU - Kamiyama, Takako

AU - Kobayashi, Michi

AU - Nishizawa, Hideyuki

PY - 1996/6

Y1 - 1996/6

N2 - Enantioselective distribution of (±)-pindolol was observed in a chloroform-boric acid two-phase system in the presence of (1R,2R)-(+)- hydrobenzoin,1,4-di-O-dodecyl L-threitol, (R)-(+)- or (S)-(-)-1,1'-2- binaphthol in the organic phase.

AB - Enantioselective distribution of (±)-pindolol was observed in a chloroform-boric acid two-phase system in the presence of (1R,2R)-(+)- hydrobenzoin,1,4-di-O-dodecyl L-threitol, (R)-(+)- or (S)-(-)-1,1'-2- binaphthol in the organic phase.

KW - binaphthol

KW - boric acid

KW - enantioseparation

KW - hydrobenzoin

KW - liquid liquid extraction

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M3 - Article

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SN - 0009-2363

VL - 44

SP - 1250

EP - 1251

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 6

ER -

Enantioselective distribution behavior of (±)-pindolol in a liquid- liquid two-phase system containing optically active diol and boric acid

Abstract

Keywords

ASJC Scopus subject areas

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