Endoscopic papillectomy for tumors of the minor duodenal papilla: A case series of six patients and literature review

Kenjiro Yamamoto, Takao Itoi, Eisuke Iwasaki, Takayoshi Tsuchiya, Kentaro Ishii, Ryosuke Tonozuka, Shuntaro Mukai, Kazumasa Nagai, Yuko Kitagawa

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Background/Purpose: Various tumors of the minor duodenal papilla have been reported, most of which are treated by laparotomy. Although early-stage tumors of the major papilla are increasingly being treated by endoscopic resection with relative ease and low invasiveness, there are only a few reports on endoscopic resection of tumors in the minor papilla. Methods: Six patients with tumors in the minor papilla were treated by endoscopic papillectomy (EP), and their clinical and histopathological data were analyzed retrospectively. Results: The final pathological diagnoses were carcinoma in adenoma in two patients and adenoma, neuroendocrine neoplasm (G1), hyperplastic lesion, and no neoplastic lesion (disappearance of adenoma after biopsy) in one patient each. En bloc resection was performed in five patients and piecemeal resection in one patient. There were no procedure-related adverse events, such as bleeding, pancreatitis, or perforation. There was one case with a residual lesion, which was treated by ablation therapy, and no recurrences during a mean follow-up of 12 ± 10.33 months (maximum, 28 months) from the date of EP. Conclusions: Endoscopic papillectomy appears to be an effective minimally invasive treatment for ampullary tumors of the minor duodenal papilla.

Original languageEnglish
Pages (from-to)1142-1150
Number of pages9
JournalJournal of Hepato-Biliary-Pancreatic Sciences
Issue number10
Publication statusPublished - 2022 Oct


  • adenocarcinoma
  • adenoma
  • endoscopic papillectomy
  • minor duodenal papilla
  • neuroendocrine neoplasm

ASJC Scopus subject areas

  • Surgery
  • Hepatology


Dive into the research topics of 'Endoscopic papillectomy for tumors of the minor duodenal papilla: A case series of six patients and literature review'. Together they form a unique fingerprint.

Cite this