Enzyme-catalyzed preparation of aliphatic polyesters containing thioester linkages

Shin Iwata, Kazunobu Toshima, Shuichi Matsumura

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)


Aliphatic polyesters containing thioester linkages were enzymatically prepared by both the copolymerization of lactone with mercaptoalkanoic acid and by the transesterification of polyesters with mercaptoalkanoic acids. The enzymatic copolymerization of ε-caprolactone with 11mercaptoundecanoic acid (11MU) and 3-mercaptopropionic acid (3MP) was performed under reduced pressure using an immobilized lipase from Candida antarctica (CA). The transesterification of poly(ε-caprolactone) and poly[(R)-3hydroxybutyrate] was carried out with 11MU and 3MP using lipase CA under reduced pressure.

Original languageEnglish
Pages (from-to)467-471
Number of pages5
JournalMacromolecular Rapid Communications
Issue number7
Publication statusPublished - 2003 May 7


  • Copolymerization/enzymes
  • Lipase-catalyzed polymerization
  • Polyesters
  • Polythioesters

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry


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