Epidermolysis bullosa acquisita in a 6-year-old Japanese boy

Kazuhiro Hayashi, Masato Ueda, Makiko Sakai, Yoshiaki Fujikawa, Kenta Tsuru, Masayuki Amagai, Masamitsu Ichihashi

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13 Citations (Scopus)


A 6-year-old Japanese boy started to develop blisters around the mouth and eyes in May 1996. With provisional diagnoses of herpes simplex or Kaposi's varicelliform eruption, he was treated with acyclovir and immune globulin. Blister formation increased, however, and he was referred to the Dermatology Clinic of Kobe University School of Medicine in August 1996. On physical examination, tense bullae and vesicles were observed on the trunk and limbs and also on the palms and soles (Fig. 1). Neither mucosal involvement nor cutaneous fragility was observed, and no nail deformity was seen. The blistering on both erythematous bases and normal skin showed a 'string-of-pearls' arrangement. Abnormal laboratory results were as follows: white blood cell count, 12.4x103/mm3 (N = 4-8.5) (eosinophils, 25%); platelets, 514x103/mm3 (N = 130-300); total protein, 4.9 g/dL.

Original languageEnglish
Pages (from-to)612-614
Number of pages3
JournalInternational Journal of Dermatology
Issue number8
Publication statusPublished - 1998
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology


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