Estimation of path length factor for measurement of haemoglobin concentration in the exposed cortical tissue

K. Sakaguchi, T. Tachibana, K. Yokoyama, S. Furukawa, E. Okada, T. Katsura, A. Maki, H. Kawaguchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The change in oxy- and deoxy haemoglobin in the cortical tissue caused by brain function can be measured from multi-spectral images of exposed cortex. We cannot ignore the wavelength dependence of mean optical path length of detected light to calculate the accurate changes in concentrations of oxy- and deoxy- haemoglobin in the cortical tissue. The optical path length factor, which reflects the wavelength dependence of mean optical path length, is experimentally estimated from the multi-spectral images of exposed cortex of guinea pigs. The optical path length factor improves the accuracy in changes in concentrations of oxy- and deoxy-haemoglobin obtained from the multi-spectral images.

Original languageEnglish
Title of host publicationEuropean Conference on Biomedical Optics, ECBO 2005
PublisherOptical Society of America
ISBN (Print)0819458635, 9780819458636
Publication statusPublished - 2005
EventEuropean Conference on Biomedical Optics, ECBO 2005 - Munich, Germany
Duration: 2005 Jun 122005 Jun 12

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701

Other

OtherEuropean Conference on Biomedical Optics, ECBO 2005
Country/TerritoryGermany
CityMunich
Period05/6/1205/6/12

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

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