Evidence-based clinical practice guidelines for management of colorectal polyps

Shinji Tanaka, Yusuke Saitoh, Takahisa Matsuda, Masahiro Igarashi, Takayuki Matsumoto, Yasushi Iwao, Yasumoto Suzuki, Hiroshi Nishida, Toshiaki Watanabe, Tamotsu Sugai, Ken ichi Sugihara, Osamu Tsuruta, Ichiro Hirata, Nobuo Hiwatashi, Hiroshi Saito, Mamoru Watanabe, Kentaro Sugano, Tooru Shimosegawa

Research output: Contribution to journalReview articlepeer-review

117 Citations (Scopus)


Background: Recently in Japan, the morbidity of colorectal polyp has been increasing. As a result, a large number of cases of colorectal polyps that are diagnosed and treated using colonoscopy has now increased, and clinical guidelines are needed for endoscopic management and surveillance after treatment.

Methods: Three committees [the professional committee for making clinical questions (CQs) and statements by Japanese specialists, the expert panelist committee for rating statements by the modified Delphi method, and the evaluating committee by moderators] were organized. Ten specialists for colorectal polyp management extracted the specific clinical statements from articles published between 1983 and September 2011 obtained from PubMed and a secondary database, and developed the CQs and statements. Basically, statements were made according to the GRADE system. The expert panel individually rated the clinical statements using a modified Delphi approach, in which a clinical statement receiving a median score greater than seven on a nine-point scale from the panel was regarded as valid.

Results: The professional committee created 91CQs and statements for the current concept and diagnosis/treatment of various colorectal polyps including epidemiology, screening, pathophysiology, definition and classification, diagnosis, treatment/management, practical treatment, complications and surveillance after treatment, and other colorectal lesions (submucosal tumors, nonneoplastic polyps, polyposis, hereditary tumors, ulcerative colitis-associated tumor/carcinoma).

Conclusions: After evaluation by the moderators, evidence-based clinical guidelines for management of colorectal polyps have been proposed for 2014.

Original languageEnglish
Pages (from-to)252-260
Number of pages9
JournalJournal of gastroenterology
Issue number3
Publication statusPublished - 2015 Mar 10
Externally publishedYes


  • Colorectal polyp
  • Colorectal tumor
  • GRADE system
  • Polyposis

ASJC Scopus subject areas

  • Gastroenterology


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