Expression and function of galectin-1 in adult neural stem cells

M. Sakaguchi; Y. Imaizumi; H. Okano

doi:10.1007/s00018-007-6476-5

Expression and function of galectin-1 in adult neural stem cells

M. Sakaguchi, Y. Imaizumi, H. Okano

Department of Physiology

Research output: Contribution to journal › Review article › peer-review

32 Citations (Scopus)

Abstract

Neural stem cells (NSCs) in the adult mammalian brain proliferate and continuously produce new neurons. To date, there has been little research into the functions of lectins in adult NSCs. Recently, we reported that a lectin, galectin-1, is expressed on adult NSCs and promotes their proliferation through its carbohydrate-binding ability. This evidence raises the possibility that glycans play roles in the proliferation of adult NSCs.

Original language	English
Pages (from-to)	1254-1258
Number of pages	5
Journal	Cellular and Molecular Life Sciences
Volume	64
Issue number	10
DOIs	https://doi.org/10.1007/s00018-007-6476-5
Publication status	Published - 2007 May 1

Keywords

Galectin
Glycan
Lectin
Neural stem cell
Subventricular zone astrocyte

ASJC Scopus subject areas

Molecular Medicine
Molecular Biology
Pharmacology
Cellular and Molecular Neuroscience
Cell Biology

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10.1007/s00018-007-6476-5

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AB - Neural stem cells (NSCs) in the adult mammalian brain proliferate and continuously produce new neurons. To date, there has been little research into the functions of lectins in adult NSCs. Recently, we reported that a lectin, galectin-1, is expressed on adult NSCs and promotes their proliferation through its carbohydrate-binding ability. This evidence raises the possibility that glycans play roles in the proliferation of adult NSCs.

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KW - Glycan

KW - Lectin

KW - Neural stem cell

KW - Subventricular zone astrocyte

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Expression and function of galectin-1 in adult neural stem cells

Abstract

Keywords

ASJC Scopus subject areas

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