Factor structure of the Japanese version of the Quality of Life in Alzheimer's Disease Scale (QOL-AD)

Takahiro Yamada; Shutaro Nakaaki; Junko Sato; Hirofumi Sato; Ryo Shikimoto; Toshi A. Furukawa; Masaru Mimura; Tatsuo Akechi

doi:10.1111/psyg.12459

Factor structure of the Japanese version of the Quality of Life in Alzheimer's Disease Scale (QOL-AD)

Takahiro Yamada, Shutaro Nakaaki, Junko Sato, Hirofumi Sato, Ryo Shikimoto, Toshi A. Furukawa, Masaru Mimura, Tatsuo Akechi

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Background: The Quality of Life in Alzheimer's Disease Scale (QOL-AD) developed by Logsdon et al. in1999 is believed to be useful for evaluating responses from both patients and their caregivers. We previously confirmed both the reliability and the validity of the Japanese version of the QOL-AD. However, the factor structure of this scale should be confirmed because the QOL-AD covers multiple facets of dementia patients’ lives. Thus, we performed a factor analysis of the Japanese QOL-AD. Then, we examined the correlations between each of the identified QOL factor scores and the results of other scales. Methods: The Japanese version of the QOL-AD was given to 132 AD patients and 132 caregivers. Four other tests were also performed at the same time: the Mini-Mental State Examination, the Neuropsychiatric Inventory (NPI), the Hyogo Activities of Daily Living Scale (HADL), and the Short Memory Questionnaire. A factor analysis using Varimax rotation was used to examine the dimensions underlying the QOL-AD. In addition, we examined the Pearson correlations between each of the identified QOL factor scores and the results of the other four tests. Results: Factor analyses of both versions of the Japanese QOL-AD (both the patients’ and the caregivers’ responses) revealed three factors that were named ‘psychological wellbeing’, ‘human relationships’, and ‘physical and social environment’. The ‘psychological wellbeing’ factor was significantly correlated with the Mood factor of the NPI. The ‘human relationships’ factor was significantly correlated with the Psychosis factor of the NPI. The ‘physical and social environment’ factor was significantly correlated with the HADL. Conclusions: Both the patients’ and the caregivers’ responses to the Japanese version of the QOL-AD were composed of three factors: ‘psychological wellbeing’, ‘human relationships’, and ‘physical and social environment’. The present results support the multi-domain concept of QOL proposed by Lawton.

Original language	English
Pages (from-to)	79-86
Number of pages	8
Journal	Psychogeriatrics
Volume	20
Issue number	1
DOIs	https://doi.org/10.1111/psyg.12459
Publication status	Published - 2020 Jan 1

Keywords

Alzheimer disease
QOL-AD
psychological wellbeing
quality of life

ASJC Scopus subject areas

Gerontology
Geriatrics and Gerontology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/psyg.12459

Cite this

@article{59f64ab98bd84153a1f95cf3e678774a,

title = "Factor structure of the Japanese version of the Quality of Life in Alzheimer's Disease Scale (QOL-AD)",

abstract = "Background: The Quality of Life in Alzheimer's Disease Scale (QOL-AD) developed by Logsdon et al. in1999 is believed to be useful for evaluating responses from both patients and their caregivers. We previously confirmed both the reliability and the validity of the Japanese version of the QOL-AD. However, the factor structure of this scale should be confirmed because the QOL-AD covers multiple facets of dementia patients{\textquoteright} lives. Thus, we performed a factor analysis of the Japanese QOL-AD. Then, we examined the correlations between each of the identified QOL factor scores and the results of other scales. Methods: The Japanese version of the QOL-AD was given to 132 AD patients and 132 caregivers. Four other tests were also performed at the same time: the Mini-Mental State Examination, the Neuropsychiatric Inventory (NPI), the Hyogo Activities of Daily Living Scale (HADL), and the Short Memory Questionnaire. A factor analysis using Varimax rotation was used to examine the dimensions underlying the QOL-AD. In addition, we examined the Pearson correlations between each of the identified QOL factor scores and the results of the other four tests. Results: Factor analyses of both versions of the Japanese QOL-AD (both the patients{\textquoteright} and the caregivers{\textquoteright} responses) revealed three factors that were named {\textquoteleft}psychological wellbeing{\textquoteright}, {\textquoteleft}human relationships{\textquoteright}, and {\textquoteleft}physical and social environment{\textquoteright}. The {\textquoteleft}psychological wellbeing{\textquoteright} factor was significantly correlated with the Mood factor of the NPI. The {\textquoteleft}human relationships{\textquoteright} factor was significantly correlated with the Psychosis factor of the NPI. The {\textquoteleft}physical and social environment{\textquoteright} factor was significantly correlated with the HADL. Conclusions: Both the patients{\textquoteright} and the caregivers{\textquoteright} responses to the Japanese version of the QOL-AD were composed of three factors: {\textquoteleft}psychological wellbeing{\textquoteright}, {\textquoteleft}human relationships{\textquoteright}, and {\textquoteleft}physical and social environment{\textquoteright}. The present results support the multi-domain concept of QOL proposed by Lawton.",

keywords = "Alzheimer disease, QOL-AD, psychological wellbeing, quality of life",

author = "Takahiro Yamada and Shutaro Nakaaki and Junko Sato and Hirofumi Sato and Ryo Shikimoto and Furukawa, {Toshi A.} and Masaru Mimura and Tatsuo Akechi",

note = "Funding Information: SN has received speaking fees from FUJIFILM RI and Mochida Seiyaku within the past 2 years. MM has received grants and/or speaker's honoraria from Daiichi-Sankyo, Dainippon-Sumitomo Pharma, Eisai, Eli Lilly, Fuji Film RI Pharma, Janssen Pharmaceutical, Mochida Pharmaceutical, MSD, Nippon Chemipher, Novartis Pharma, Ono Yakuhin, Otsuka Pharmaceutical, Pfizer, Takeda Yakuhin, Tsumura, and Yoshitomi Yakuhin within the past 3 years. TA has received lectures fees from Astellas, AstraZeneca, Daiichi-Sankyo, Dainippon-Sumitomo, Eizai, Hisamitsu, Lilly, MSD, Meiji-seika Pharma, Mochida, Mundipharma, Otsuka, Shionogi, and Terumo. He has received research funds from Daiichi-Sankyo, Eizai, MSD, Pfizer, Novartis, and Tanabe-Mitsubishi. TAF has received lecture fees from Meiji, Mitsubishi-Tanabe, MSD and Pfizer. He has received research support from Mitsubishi-Tanabe. Publisher Copyright: {\textcopyright} 2019 Japanese Psychogeriatric Society",

year = "2020",

month = jan,

day = "1",

doi = "10.1111/psyg.12459",

language = "English",

volume = "20",

pages = "79--86",

journal = "Psychogeriatrics",

issn = "1346-3500",

publisher = "Wiley-Blackwell",

number = "1",

}

TY - JOUR

T1 - Factor structure of the Japanese version of the Quality of Life in Alzheimer's Disease Scale (QOL-AD)

AU - Yamada, Takahiro

AU - Nakaaki, Shutaro

AU - Sato, Junko

AU - Sato, Hirofumi

AU - Shikimoto, Ryo

AU - Furukawa, Toshi A.

AU - Mimura, Masaru

AU - Akechi, Tatsuo

N1 - Funding Information: SN has received speaking fees from FUJIFILM RI and Mochida Seiyaku within the past 2 years. MM has received grants and/or speaker's honoraria from Daiichi-Sankyo, Dainippon-Sumitomo Pharma, Eisai, Eli Lilly, Fuji Film RI Pharma, Janssen Pharmaceutical, Mochida Pharmaceutical, MSD, Nippon Chemipher, Novartis Pharma, Ono Yakuhin, Otsuka Pharmaceutical, Pfizer, Takeda Yakuhin, Tsumura, and Yoshitomi Yakuhin within the past 3 years. TA has received lectures fees from Astellas, AstraZeneca, Daiichi-Sankyo, Dainippon-Sumitomo, Eizai, Hisamitsu, Lilly, MSD, Meiji-seika Pharma, Mochida, Mundipharma, Otsuka, Shionogi, and Terumo. He has received research funds from Daiichi-Sankyo, Eizai, MSD, Pfizer, Novartis, and Tanabe-Mitsubishi. TAF has received lecture fees from Meiji, Mitsubishi-Tanabe, MSD and Pfizer. He has received research support from Mitsubishi-Tanabe. Publisher Copyright: © 2019 Japanese Psychogeriatric Society

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Background: The Quality of Life in Alzheimer's Disease Scale (QOL-AD) developed by Logsdon et al. in1999 is believed to be useful for evaluating responses from both patients and their caregivers. We previously confirmed both the reliability and the validity of the Japanese version of the QOL-AD. However, the factor structure of this scale should be confirmed because the QOL-AD covers multiple facets of dementia patients’ lives. Thus, we performed a factor analysis of the Japanese QOL-AD. Then, we examined the correlations between each of the identified QOL factor scores and the results of other scales. Methods: The Japanese version of the QOL-AD was given to 132 AD patients and 132 caregivers. Four other tests were also performed at the same time: the Mini-Mental State Examination, the Neuropsychiatric Inventory (NPI), the Hyogo Activities of Daily Living Scale (HADL), and the Short Memory Questionnaire. A factor analysis using Varimax rotation was used to examine the dimensions underlying the QOL-AD. In addition, we examined the Pearson correlations between each of the identified QOL factor scores and the results of the other four tests. Results: Factor analyses of both versions of the Japanese QOL-AD (both the patients’ and the caregivers’ responses) revealed three factors that were named ‘psychological wellbeing’, ‘human relationships’, and ‘physical and social environment’. The ‘psychological wellbeing’ factor was significantly correlated with the Mood factor of the NPI. The ‘human relationships’ factor was significantly correlated with the Psychosis factor of the NPI. The ‘physical and social environment’ factor was significantly correlated with the HADL. Conclusions: Both the patients’ and the caregivers’ responses to the Japanese version of the QOL-AD were composed of three factors: ‘psychological wellbeing’, ‘human relationships’, and ‘physical and social environment’. The present results support the multi-domain concept of QOL proposed by Lawton.

AB - Background: The Quality of Life in Alzheimer's Disease Scale (QOL-AD) developed by Logsdon et al. in1999 is believed to be useful for evaluating responses from both patients and their caregivers. We previously confirmed both the reliability and the validity of the Japanese version of the QOL-AD. However, the factor structure of this scale should be confirmed because the QOL-AD covers multiple facets of dementia patients’ lives. Thus, we performed a factor analysis of the Japanese QOL-AD. Then, we examined the correlations between each of the identified QOL factor scores and the results of other scales. Methods: The Japanese version of the QOL-AD was given to 132 AD patients and 132 caregivers. Four other tests were also performed at the same time: the Mini-Mental State Examination, the Neuropsychiatric Inventory (NPI), the Hyogo Activities of Daily Living Scale (HADL), and the Short Memory Questionnaire. A factor analysis using Varimax rotation was used to examine the dimensions underlying the QOL-AD. In addition, we examined the Pearson correlations between each of the identified QOL factor scores and the results of the other four tests. Results: Factor analyses of both versions of the Japanese QOL-AD (both the patients’ and the caregivers’ responses) revealed three factors that were named ‘psychological wellbeing’, ‘human relationships’, and ‘physical and social environment’. The ‘psychological wellbeing’ factor was significantly correlated with the Mood factor of the NPI. The ‘human relationships’ factor was significantly correlated with the Psychosis factor of the NPI. The ‘physical and social environment’ factor was significantly correlated with the HADL. Conclusions: Both the patients’ and the caregivers’ responses to the Japanese version of the QOL-AD were composed of three factors: ‘psychological wellbeing’, ‘human relationships’, and ‘physical and social environment’. The present results support the multi-domain concept of QOL proposed by Lawton.

KW - Alzheimer disease

KW - QOL-AD

KW - psychological wellbeing

KW - quality of life

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Factor structure of the Japanese version of the Quality of Life in Alzheimer's Disease Scale (QOL-AD)

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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