This paper describes a fiber-shaped microscale tissue with blood vessel networks. We co-cultured Hep-G2 (Human hepatic epithelial cell line) and HUVEC (human umbilical endothelial cell) in a collagen/alginate core-shell hydrogel microfiber fabricated by using a microfluidic device. We observed difference in construction of blood vessel networks in the hepatic tissue by varying in the ratio of co-cultured cells and the diameter of the core. In addition, by arranging the fiber-shaped tissues to construct macroscale tissue assembly, we confirmed the connection of blood vessel networks between the assembled fiber-shaped tissues.
|Title of host publication
|2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017
|Institute of Electrical and Electronics Engineers Inc.
|Number of pages
|Published - 2017 Feb 23
|30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017 - Las Vegas, United States
Duration: 2017 Jan 22 → 2017 Jan 26
|Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
|30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017
|17/1/22 → 17/1/26
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Mechanical Engineering
- Electrical and Electronic Engineering