Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer

Kenkichi Sasaki, Ayako Oyane, Koji Hyodo, Atsuo Ito, Yu Sogo, Masanobu Kamitakahara, Koji Ioku

Research output: Contribution to journalArticlepeer-review


A composite layer of fibroblast growth factor-2 (FGF-2) and low-crystalline apatite was formed on an ethylene-vinyl alcohol copolymer specimen using two types of aqueous calcium phosphate solutions supplemented with 10 μg·mL-1 FGF-2; one is a CP solution that is prepared by dissolving chemical reagents into ultrapure water and the other is an RKB solution that can be prepared by mixing clinically approved infusion fluids. In both solutions, a sufficient amount of FGF-2 for new skin tissue formation (1 μg·cm-2) was immobilized on the specimen surface.

Original languageEnglish
Pages (from-to)455-458
Number of pages4
JournalKey Engineering Materials
Volume361-363 I
Publication statusPublished - 2008 Jan 1
Externally publishedYes


  • Apatite
  • Bacterial infection
  • Composite
  • Ethylene-vinyl alcohol copolymer
  • FGF-2

ASJC Scopus subject areas

  • General Materials Science
  • Mechanics of Materials
  • Mechanical Engineering


Dive into the research topics of 'Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer'. Together they form a unique fingerprint.

Cite this