Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer

Kenkichi Sasaki; Ayako Oyane; Koji Hyodo; Atsuo Ito; Yu Sogo; Masanobu Kamitakahara; Koji Ioku

Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer

Kenkichi Sasaki, Ayako Oyane, Koji Hyodo, Atsuo Ito, Yu Sogo, Masanobu Kamitakahara, Koji Ioku

Research output: Contribution to journal › Article › peer-review

Abstract

A composite layer of fibroblast growth factor-2 (FGF-2) and low-crystalline apatite was formed on an ethylene-vinyl alcohol copolymer specimen using two types of aqueous calcium phosphate solutions supplemented with 10 μg·mL^-1 FGF-2; one is a CP solution that is prepared by dissolving chemical reagents into ultrapure water and the other is an RKB solution that can be prepared by mixing clinically approved infusion fluids. In both solutions, a sufficient amount of FGF-2 for new skin tissue formation (1 μg·cm^-2) was immobilized on the specimen surface.

Original language	English
Pages (from-to)	455-458
Number of pages	4
Journal	Key Engineering Materials
Volume	361-363 I
Publication status	Published - 2008 Jan 1
Externally published	Yes

Keywords

Apatite
Bacterial infection
Composite
Ethylene-vinyl alcohol copolymer
FGF-2

ASJC Scopus subject areas

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

Cite this

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title = "Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer",

abstract = "A composite layer of fibroblast growth factor-2 (FGF-2) and low-crystalline apatite was formed on an ethylene-vinyl alcohol copolymer specimen using two types of aqueous calcium phosphate solutions supplemented with 10 μg·mL-1 FGF-2; one is a CP solution that is prepared by dissolving chemical reagents into ultrapure water and the other is an RKB solution that can be prepared by mixing clinically approved infusion fluids. In both solutions, a sufficient amount of FGF-2 for new skin tissue formation (1 μg·cm-2) was immobilized on the specimen surface.",

keywords = "Apatite, Bacterial infection, Composite, Ethylene-vinyl alcohol copolymer, FGF-2",

author = "Kenkichi Sasaki and Ayako Oyane and Koji Hyodo and Atsuo Ito and Yu Sogo and Masanobu Kamitakahara and Koji Ioku",

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T1 - Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer

AU - Sasaki, Kenkichi

AU - Oyane, Ayako

AU - Hyodo, Koji

AU - Ito, Atsuo

AU - Sogo, Yu

AU - Kamitakahara, Masanobu

AU - Ioku, Koji

PY - 2008/1/1

Y1 - 2008/1/1

N2 - A composite layer of fibroblast growth factor-2 (FGF-2) and low-crystalline apatite was formed on an ethylene-vinyl alcohol copolymer specimen using two types of aqueous calcium phosphate solutions supplemented with 10 μg·mL-1 FGF-2; one is a CP solution that is prepared by dissolving chemical reagents into ultrapure water and the other is an RKB solution that can be prepared by mixing clinically approved infusion fluids. In both solutions, a sufficient amount of FGF-2 for new skin tissue formation (1 μg·cm-2) was immobilized on the specimen surface.

AB - A composite layer of fibroblast growth factor-2 (FGF-2) and low-crystalline apatite was formed on an ethylene-vinyl alcohol copolymer specimen using two types of aqueous calcium phosphate solutions supplemented with 10 μg·mL-1 FGF-2; one is a CP solution that is prepared by dissolving chemical reagents into ultrapure water and the other is an RKB solution that can be prepared by mixing clinically approved infusion fluids. In both solutions, a sufficient amount of FGF-2 for new skin tissue formation (1 μg·cm-2) was immobilized on the specimen surface.

KW - Apatite

KW - Bacterial infection

KW - Composite

KW - Ethylene-vinyl alcohol copolymer

KW - FGF-2

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SN - 1013-9826

VL - 361-363 I

SP - 455

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JO - Key Engineering Materials

JF - Key Engineering Materials

ER -

Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer

Abstract

Keywords

ASJC Scopus subject areas

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