Four-dimensional ct analysis using sequential 3d-3d registration

Satoshi Oki, Kazuya Kaneda, Yoshitake Yamada, Minoru Yamada, Yutaro Morishige, Kengo Harato, Noboru Matsumura, Takeo Nagura, Masahiro Jinzaki

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Four-dimensional computed tomography (4DCT) provides a series of volume data and visualizes joint motions. However, numerical analysis of 4DCT data remains difficult because segmentation in all volumetric frames is time-consuming. We aimed to analyze joint kinematics using a sequential 3D-3D registration technique to provide the kinematics of the moving bone with respect to the fixed bone semiautomatically using 4DCT DICOM data and existing software. Surface data of the source bones are reconstructed from 3DCT. The trimmed surface data are respectively matched with surface data from the first frame in 4DCT. These trimmed surfaces are sequentially matched until the last frame. These processes provide positional information for target bones in all frames of the 4DCT. Once the coordinate systems of the target bones are decided, translation and rotation angles between any two bones can be calculated. This 4DCT analysis offers advantages in kinematic analyses of complex structures such as carpal or tarsal bones. However, fast or large-scale motions cannot be traced because of motion artifacts.

Original languageEnglish
Article numbere59857
JournalJournal of Visualized Experiments
Issue number153
Publication statusPublished - 2019 Nov


  • 4DCT
  • Bioengineering
  • Computed tomography
  • Image analysis
  • Issue 153
  • Joint kinematics
  • Motion analysis
  • Surface registration

ASJC Scopus subject areas

  • General Neuroscience
  • General Chemical Engineering
  • General Biochemistry,Genetics and Molecular Biology
  • General Immunology and Microbiology


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