Four hepatosplenic T-cell lymphoma cases of Japanese patients

Hidetsugu Kawai, Hiromichi Matsushita, Ken Ohmachi, Minoru Kojima, Shinichiro Machida, Yoshiaki Ogawa, Hiroshi Kawada, Naoya Nakamura, Kiyoshi Ando

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an elderly case that was 74 years of age, were not at adolescence. No cases had a history of immunodeficiency. All other disease phenotypes were similar to the typical HSTCL cases. These findings suggest that there are a certain proportion of HSTCL patients who presented after middle age.

Original languageEnglish
Pages (from-to)3-6
Number of pages4
JournalLeukemia Research Reports
Publication statusPublished - 2016
Externally publishedYes


  • Elderly patients
  • Hepatosplenic T-cell lymphoma
  • Immunodeficiency

ASJC Scopus subject areas

  • Hematology
  • Oncology


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