Abstract
Epithelial cells are closely connected to each other and to the extracellular matrix by a set of adhesive contacts that provide tissues with unique barrier properties and play a prominent role in cell morphology, tissue physiology, and cell signaling. This review highlights advances made in understanding the contributions of galectin-3, a carbohydrate-binding protein with affinity toward β-galactosides, as a modulator of epithelial junction assembly and function. The interactions of galectin-3 within adhesive structures are discussed in relation to wound healing and tumor progression.
| Original language | English |
|---|---|
| Pages (from-to) | 1-6 |
| Number of pages | 6 |
| Journal | Tissue Barriers |
| Volume | 3 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2015 Jul 3 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- cancer
- epithelial junction
- galectin-3
- matrix metalloproteinases
- wound healing
ASJC Scopus subject areas
- Biochemistry
- Histology
- Cell Biology
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