Genetic analysis of nothoapioi formation in Perilla frutescens

Michiho Ito, Mariko Toyoda, Akiko Yuba, Gisho Honda

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)


A new essential oil chemotype of Perilla frutescens was found in that plant variety from Che-ju island in Korea. The steam-distilled oil of this plant was examined by GC-MS and 32 compounds were identified. Its principal constituents were β-caryophyllene, dillapiol and nothoapiol. Also, crossing experiments were performed between the new chemotype and known chemotypes to clarify the genetic control of the production of nothoapiol. The gene Na, which promotes conversion from dillapiol to nothoapiol, was suggested, and was considered to be closely linked with the allele D.

Original languageEnglish
Pages (from-to)598-601
Number of pages4
JournalBiological and Pharmaceutical Bulletin
Issue number6
Publication statusPublished - 1999 Jun
Externally publishedYes


  • Essential oil
  • GC-MS
  • Genetic control
  • Nothoapiol
  • Perilla frutescens

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science


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