TY - JOUR
T1 - Genetic Protective Factors for Dementia Isolated by Centenarian Researches
AU - Sasaki, Takashi
AU - Nishimoto, Yoshinori
AU - Hirose, Nobuyoshi
AU - Arai, Yasumichi
PY - 2019/10/1
Y1 - 2019/10/1
N2 - Due to the recent rapid increase in the number of elderly people in the world, health management and maintenance in elderly people have become important issues. Centenaria, who are older than 100 years, tend to stay independent in their daily life with maintenance of cognitive function until the later stage of their life compared with elderly people who die earlier. In this review, we summarize the characteristics of centenarians, the genetic risk and protective factors for longevity, and intersections between research on centenarians and dementia research.
AB - Due to the recent rapid increase in the number of elderly people in the world, health management and maintenance in elderly people have become important issues. Centenaria, who are older than 100 years, tend to stay independent in their daily life with maintenance of cognitive function until the later stage of their life compared with elderly people who die earlier. In this review, we summarize the characteristics of centenarians, the genetic risk and protective factors for longevity, and intersections between research on centenarians and dementia research.
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U2 - 10.11477/mf.1416201405
DO - 10.11477/mf.1416201405
M3 - Review article
C2 - 31588050
AN - SCOPUS:85072931873
SN - 1881-6096
VL - 71
SP - 1061
EP - 1070
JO - Brain and nerve = Shinkei kenkyu no shinpo
JF - Brain and nerve = Shinkei kenkyu no shinpo
IS - 10
ER -