Glutamate-induced deporalization in earthworm ventral nerve cord

Kotaro Oka, Hiroto Ogawa, Shozo Fujita

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


We investigated glutamate-induced neuron response in the ventral nerve cord of the earthworm (Eisenia foetida) using a voltage-sensitive dye-imaging technique. Isolated earthworm ganglia were stained by fluorescence voltage-sensitive dye, RH414, and voltage image was acquired by a conventional charge-coupled device (CCD) technique or a confocal laser scanning microscope. The fluorescence images before and during the glutamate stimulation was acquired and the relative fluorescence change was imaged as pseudo-color. Bath-applied glutamate (1 mM) depolarized many neurons on the ventral side, and in the three giant fibers on the dorsal side.

Original languageEnglish
Pages (from-to)41-44
Number of pages4
JournalNeuroscience Letters
Issue number1-2
Publication statusPublished - 1994 Sept 26
Externally publishedYes


  • Earthworm
  • Glutamate receptor
  • Lateral giant fiber
  • Median giant fiber
  • Optical recording
  • Voltage-sensitive dye

ASJC Scopus subject areas

  • Neuroscience(all)


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