Guidelines for endoscopic submucosal dissection and endoscopic mucosal resection for early gastric cancer (second edition)

Hiroyuki Ono, Kenshi Yao, Mitsuhiro Fujishiro, Ichiro Oda, Noriya Uedo, Satoshi Nimura, Naohisa Yahagi, Hiroyasu Iishi, Masashi Oka, Yoichi Ajioka, Kazuma Fujimoto

Research output: Contribution to journalArticlepeer-review

170 Citations (Scopus)


In response to the rapid and wide acceptance and use of endoscopic treatments for early gastric cancer, the Japan Gastroenterological Endoscopy Society, in collaboration with the Japanese Gastric Cancer Association, produced “Guidelines for Endoscopic Submucosal Dissection and Endoscopic Mucosal Resection for Early Gastric Cancer” in 2014, as a set of basic guidelines in accordance with the principles of evidence-based medicine. At the time, a number of statements had to be established by consensus (the lowest evidence level), as evidence levels remained low for many specific areas in this field. However, in recent years, the number of well-designed clinical studies has been increasing. Based on new findings, we have issued the revised second edition of the above guidelines that cover the present state of knowledge. These guidelines are divided into the following seven categories: indications, preoperative diagnosis, techniques, evaluation of curability, complications, long-term postoperative surveillance, and histology.

Original languageEnglish
Pages (from-to)4-20
Number of pages17
JournalDigestive Endoscopy
Issue number1
Publication statusPublished - 2021 Jan
Externally publishedYes


  • early gastric cancer
  • endoscopic mucosal resection
  • endoscopic submucosal dissection
  • evidence-based guidelines

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology


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