Haploidentical hematopoietic cell transplantation for disseminated Ewing sarcoma

Hiroki Yoshihara, Tadashi Kumamoto, Rintaro Ono, Keiko Akahane, Taiki Nozaki, Shogo Kobayashi, Atsushi Kikuta, Seiichi Matsumoto, Daisuke Hasegawa, Chitose Ogawa, Atsushi Manabe

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We describe the case of a 13-year-old girl with multifocal disseminated Ewing sarcoma family of tumor (ESFT) who received a 5/8 human leukocyte antigen-matched haploidentical hematopoietic cell transplantation to generate a graft-versus-tumor effect. The patient had grade 2 acute graft-versus-host disease (GVHD) of the skin and chronic GVHD nausea and abdominal pain that required prednisolone for 17 months, but has been free from ESFT for 3 years 10 months after therapy. The present case suggests a beneficial effect of haploidentical hematopoietic cell transplantation in disseminated ESFT.

Original languageEnglish
Pages (from-to)223-226
Number of pages4
JournalPediatrics International
Volume59
Issue number2
DOIs
Publication statusPublished - 2017 Feb 1
Externally publishedYes

Keywords

  • Ewing sarcoma
  • graft-versus-host disease
  • graft-versus-tumor effect
  • hematopoietic stem cell transplantation
  • killer cell immunoglobulin-like receptor

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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