Haterumaimides A-E, five new dichlorolissoclimide-type diterpenoids from an ascidian, Lissoclinum sp.

Md Jasim Uddin; Susumu Kokubo; Kiyotake Suenaga; Katsuhiro Ueda; Daisuke Uemura

doi:10.3987/com-00-s(i)100

Haterumaimides A-E, five new dichlorolissoclimide-type diterpenoids from an ascidian, Lissoclinum sp.

Md Jasim Uddin, Susumu Kokubo, Kiyotake Suenaga, Katsuhiro Ueda, Daisuke Uemura

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

Five new dichlorolissoclimide-type diterpenoids, haterumaimides A-E, were isolated from an ascidian, Lissoclinum sp., and the absolute stereostructures of haterumaimides A-D and the relative stereostructure of haterumaimide E were determined by spectroscopic and chemical analyses. Haterumaimides A-E inhibited the first cleavage of fertilized sea urchin eggs and exhibited cytotoxicity against P388 cells.

Original language	English
Pages (from-to)	1039-1047
Number of pages	9
Journal	Heterocycles
Volume	54
Issue number	2
DOIs	https://doi.org/10.3987/com-00-s(i)100
Publication status	Published - 2001 Feb 1
Externally published	Yes

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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AU - Suenaga, Kiyotake

AU - Ueda, Katsuhiro

AU - Uemura, Daisuke

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Haterumaimides A-E, five new dichlorolissoclimide-type diterpenoids from an ascidian, Lissoclinum sp.

Abstract

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