TY - JOUR
T1 - Helicobacter cinaedi bacteremia with cellulitis after ABO-incompatible living-donor liver transplantation
T2 - Case report
AU - Mishima, Kohei
AU - Obara, Hideaki
AU - Sugita, Kayoko
AU - Shinoda, Masahiro
AU - Kitago, Minoru
AU - Abe, Yuta
AU - Hibi, Taizo
AU - Yagi, Hiroshi
AU - Matsubara, Kentaro
AU - Mori, Takehiko
AU - Takano, Yaoko
AU - Fujiwara, Hiroshi
AU - Itano, Osamu
AU - Hasegawa, Naoki
AU - Iwata, Satoshi
AU - Kitagawa, Yuko
N1 - Publisher Copyright:
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
PY - 2015/7/1
Y1 - 2015/7/1
N2 - Helicobacter cinaedi (H. cinaedi), a Gram-negative spiral-shaped bacterium, is an enterohepatic non-Helicobacter pylori Helicobacter species. We report the first case of H. cinaedi bacteremia with cellulitis after liver transplantation. A 48-year-old male, who had been a dog breeder for 15 years, underwent ABO-incompatible living-donor liver transplantation for hepatitis C virus-induced decompensated cirrhosis using an anti-hepatitis B core antibody-positive graft. The patient was preoperatively administered rituximab and underwent plasma exchange twice to overcome blood type incompatibility. After discharge, he had been doing well with immunosuppression therapy comprising cyclosporine, mycophenolate mofetil, and steroid according to the ABO-incompatible protocol of our institution. However, 7 mo after transplantation, he was admitted to our hospital with a diagnosis of recurrent cellulitis on the left lower extremity, and H. cinaedi was detected by both blood culture and polymerase chain reaction analysis. Antibiotics improved his symptoms, and he was discharged at day 30 after admission. Clinicians should be more aware of H. cinaedi in immunocompromised patients, such as ABO-incompatible transplant recipients.
AB - Helicobacter cinaedi (H. cinaedi), a Gram-negative spiral-shaped bacterium, is an enterohepatic non-Helicobacter pylori Helicobacter species. We report the first case of H. cinaedi bacteremia with cellulitis after liver transplantation. A 48-year-old male, who had been a dog breeder for 15 years, underwent ABO-incompatible living-donor liver transplantation for hepatitis C virus-induced decompensated cirrhosis using an anti-hepatitis B core antibody-positive graft. The patient was preoperatively administered rituximab and underwent plasma exchange twice to overcome blood type incompatibility. After discharge, he had been doing well with immunosuppression therapy comprising cyclosporine, mycophenolate mofetil, and steroid according to the ABO-incompatible protocol of our institution. However, 7 mo after transplantation, he was admitted to our hospital with a diagnosis of recurrent cellulitis on the left lower extremity, and H. cinaedi was detected by both blood culture and polymerase chain reaction analysis. Antibiotics improved his symptoms, and he was discharged at day 30 after admission. Clinicians should be more aware of H. cinaedi in immunocompromised patients, such as ABO-incompatible transplant recipients.
KW - Aboincompatible
KW - Bacteremia
KW - Cellulitis
KW - HBc-Ab-positive donor
KW - Helicobacter cinaedi
KW - Hepatitis C
KW - Liver transplantation
KW - Living-donor
UR - http://www.scopus.com/inward/record.url?scp=84936797764&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84936797764&partnerID=8YFLogxK
U2 - 10.3748/wjg.v21.i25.7911
DO - 10.3748/wjg.v21.i25.7911
M3 - Article
C2 - 26167092
AN - SCOPUS:84936797764
SN - 1007-9327
VL - 21
SP - 7911
EP - 7915
JO - World Journal of Gastroenterology
JF - World Journal of Gastroenterology
IS - 25
ER -
